Lilly Icos LLC

Juerg Lareida

Compounds of formula (I) in which R=Calkyl, optionally halosubstituted; R=H, Calkyl, optionally halosubstituted or replaced by halogen; R=Calkyl, optionally halosubstituted; R=SONRR, CORor halogen, Calkenyl; optionally substituted with NRR, SONRR, CONRR, CORor halogen, Calkanoyl, optionally substituted with NRR, SONRR, CONRR, CORor halogen; Rand R=independently H or Calkyl, or, together with the N atom to which they are attached, a pyrrolidino, piperidino, morpholino, 4-(NR)-1-piperazinyl or 1-imidazolyl ring optionally substituted with one or two Calkyl groups; R=H, Calkyl, optionally fluorosubstituted, and R=H,Calkyl or hydroxyalkyl with 1-4 C atoms, or the pharmaceutically acceptable salts thereof are useful for the chemotherapeutic treatment of neuropathies.

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Aarau, Switzerland

Juerg Lareida