The Gillette Company

Other

Judith Wolfe Laney

Virginia Streusand Goldman

Charles W Slife

Disclosed are &agr;-amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, threonine amides, glycine amides, serine amides, and alanine amides can be used in the invention. Such &agr;-amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the &agr;-amides of L-amino acids by bacteria in axillae. The &agr;-amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.

&agr;-amides of L-amino acid as fragrance precursors

Disclosed are .alpha.-amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, glutamine and asparagine amides can be used in the invention. Such .alpha.-amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the .alpha.-amides of L-amino acids by bacteria in axillae. The .alpha.-amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.

.alpha.-amides of L-amino acids as fragrance precursors

The invention relates to a method for reducing malodor, preferably by generating a pleasant odor, in the axilla utilizing a deodorant composition containing a competitive substrate for the malodor producing enzyme. Upon cleavage by the malodor producing enzyme, the compounds of the present invention result in byproducts which produce either a neutral or a pleasant odor. The compound is present in a dermatologically acceptable vehicle, and in an amount effective to produce either a neutral or a pleasant odor. The present invention also relates to novel O-acylated serine and threonine compounds and method for the production thereof.

O-acyl serines and threonines as deodorants

The invention relates to a method of suppressing human body malodor by utilizing a deodorant composition containing a competitive substrate for the enzymatic creation of axillary body malodor. The compound is present in a dermatologically acceptable vehicle, and in an amount effective to reduce the conversion of malodor producing precursor. The present invention also relates to novel O-acylated serine compounds and method for the production thereof.

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Silver Spring, MD, United States of America

Judith Wolfe Laney