Novartis Ag

Judith Schaefer

Peter Marbach

Francois Legay

Rainer Hillenbrand

Jean-Michel Grenet

Patrick Albientz

Severine Marrony

A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents and derivatives. Furthermore, drug monitoring assays using said binding agents for monitoring pharmaceutically active forms of said parent compound are provided.

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Liestal/BL, Switzerland

Judith Schaefer