University of British Columbia

Promis Neurosciences Inc.

Judith Maxwell Silverman

Neil R Cashman

Johanne Kaplan

Steven S Plotkin

Ebrima Gibbs

The disclosure pertains to antibodies that bind A-beta oligomers and methods of making and using said antibodies. Also provided are chimeric or humanized antibodies, including antibodies having CDRs in Table 2 and/or having a sequence as set forth in Table 4B or a sequence with at least 50% sequence identity thereto optionally wherein the CDR amino acid sequences are as set for forth in SEQ ID Nos: 74-79. Also provided are methods and uses thereof as well as kits comprising said antibodies.

Humanized antibodies binding to amyloid-beta (A-beta)

The disclosure pertains to antibodies that bind A-beta oligomers and methods of making and using said antibodies.

Growing community of inventors

Whistler, Canada

Judith Maxwell Silverman