Impulse Dynamics Nv

Impulse Dynamics (israel) Ltd.

Judith Kornfeld

Nissim Darvish

Bella Felsen

Shlomo Ben-Haim

Yuval Mika

Maier Fenster

Itzhak Shemer

Dov Malonek

Itzik Shemer

A method of modifying the force of contraction of at least a portion of a heart chamber is provided. A non-excitatory electric field of given duration is applied, at a delay after an activation of the heart, which increase the force of contraction by at least 5%. Apparatus is also provided for pacing with hemodynamic improvement. Circuitry applies an extended pacing signal to electrodes to pace the heart, the extended pacing signal having an overall duration greater than 8 ms from a time of initiation of application of that portion of the signal that initiates action potential propagation. The signal includes a train of biphasic pulses having pulse durations of at least 1 ms, and the signal has an amplitude that is at least three times as great as a threshold for pacing the heart and that is sufficient neither for cardioversion nor for defibrillation. Other embodiments are also described.

Electrical muscle controller and pacing with hemodynamic enhancement

Apparatus () for heart pacing with hemodynamic improvement, including one or more electrodes (), which convey electrical signals to respective cardiac muscle segments. Signal generation circuitry () applies an extended pacing signal (), having an overall duration greater than three times a chronaxie time, to the one or more electrodes so as to pace the heart. The signal preferably includes a train of a plurality of biphasic pulses, and has an amplitude at least three times as great as a threshold for pacing the heart, but not sufficient for cardioversion.

Pacing with hemodynamic enhancement

This invention is a lead () for modifying the activity of a tissue, particularly the heart. Electrodes are provided for performing sensing () (), and/or signal delivery () () functions. A control unit controls the parameters of the electric field provided by signal delivery electrodes to prevent the generation of a propagation action potential in the tissue.

Multi-electrode lead

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Haifa, Israel

Judith Kornfeld