Centaur Pharmaceuticals, Inc.

Judith A Kelleher

Yong-Kang Zhang

Kirk R Maples

Allan L Wilcox

Lowell David Waterbury

Julian Levell

Alina Dykman

Hong Xu

Disclosed are novel &agr;-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.

Alpha-(4-Ethoxyphenyl)-N-tert-butylnitrone, pharmaceutical compositions and their medical use

Disclosed are novel aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.

&agr;-aryl-N-alkylnitrones and pharmaceutical compositions containing the same

Disclosed are furan nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compounds are useful as analytical reagents for detecting free radicals and as therapeutics for treating a wide variety of medical dysfunctions and diseases.

Furan nitrone compounds

Disclosed are methods for preventing the onset of autoimmune or inflammatory diseases in mammals using a pharmaceutical composition containing a pharmaceutically acceptable carrier and an effective amount of a thioether furan nitrone compound.

Methods for preventing and treating autoimmune and inflammatory disease using thioether furan nitrone compounds

Disclosed are methods for preventing and/or treating autoimmune and inflammatory diseases in mammals using a pharmaceutical composition containing a pharmaceutically acceptable carrier and an effective amount of a thiether furan nitrone compound.

Methods for preventing and treating autoimmune and inflammatory diseases

Disclosed are methods for treating a patient with an acute central nervous system or cardiovascular disorder or a neurodegenerative, autoimmune or inflammatory disease using a pharmaceutical composition containing a pharmaceutically acceptable carrier and an effective amount of a furan nitrone compound.

Methods for treating medical dysfunctions and diseases using furan

Disclosed are novel .alpha.-aryl-N-alkylnitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.

.alpha.-aryl-N-alkylnitrones and pharmaceutical compositions containing

Disclosed are novel thiophene nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.

Thiophene nitrone compounds

Disclosed are novel thioether furan nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals and as analytical reagents for detecting free radicals.

Thioether furan nitrone compounds

Disclosed are furansulfonic acid derivatives and pharmaceutical compositions containing such derivatives. The disclosed compositions are useful for preventing and/or treating neurodegenerative, autoimmune and inflammatory conditions in mammals.

Growing community of inventors

Fremont, CA, United States of America

Judith A Kelleher