Richter Gedeon Vegyeszeti Gyar Rt

Judit Kosary

Endre Kasztreiner

Gyorgy Cseh

Istvan Elekes

Laszlo Tardos

Laszlo Jaszlits

Peter Matyus

Edit Kosa

Agnes Kenessey

Zsuzsa Huszti

Sandor Elek

Istvan Polgari

Geza Szilagyi

Janos Borvendeg

Laszlo Nagy

Maria Kuhar Nee Kurthy

Nandor Makk

Klara Czako

Eszter Diesler

Gyongyi Nagy Nee Csokas

Zsuzsanna Huszti

Gabriella Kiss

Erzsebet Szuucs

Veronika Szilagyi Nee Pap

Judit Stverteczky Nee Sztrokay

Gyorgy Rablocsky

Ildiko Pribusz Nee Rapp

Laszlo Kaufer

Szilagyi Geza

Judit Kincsessy

The invention relates to novel 3(2H)-pyridazinone-derivatives of the general formula (I), pharmaceutical compositions containing them and process for their preparation. In the general formula (I) ##STR1## stands for an ethyl or propyl group substituted by a terminal halogen atom or a hydroxyl or NR.sup.1 R.sup.2 group, wherein

3(2H)-pyridazinones and pharmaceutical compositions thereof

Pyridazinylhydrazones capable of lowering blood pressure have the formula ##STR1## wherein R.sup.1 is hydrogen, chlorine, alkyl having from 1 to 4 carbon atoms, methoxy, hydroxyl, carbamoyl or cyano;

Novel pyridazinylhydrazones and method of administering same

A pharmaceutical compositions with hypotensive effects which comprise a compound of formula (I) or a pharmaceutically acceptable acid addition salt thereof, ##STR1## wherein R.sup.1 is formula (II) ##STR2## wherein R.sup.4 and R.sup.5 each represent hydrogen, hydroxy, nitro at the same time

Compositions with potentiated hypotensive effects

Pyridazinylhydrazones capable of lowering blood pressure having the formula ##STR1## wherein R.sup.1 is hydrogen, chlorine, alkyl having from 1 to 4 carbon atoms, methoxy, hydroxyl, carbamoyl or cyano;

Morpholino pyridazinylhydrazones

The invention relates to novel sulfonamidobenzoic acid derivatives having the general formula ##STR1## wherein R.sup.1 denotes a C.sub.1-4 alkoxy group or a hydrazino group or an NR.sup.4 R.sup.5 group, wherein R.sup.4 and R.sup.5 denote each a hydrogen atom or an identical or different C.sub.1-4 alkyl group; furthermore R.sup.4 may denote an aralkyl or substituted aralkyl group provided that R.sup.5 denotes a hydrogen atom; furthermore NR.sup.4 R.sup.5 may denote a morpholine or piperazine ring;

Sulfonamido-benzoic acid derivatives

Growing community of inventors

Budapest, Hungary

Judit Kosary