Invitrogen Corporation

Genicon Sciences Corporation

Other

Juan Yguerabide

Evangelina E Yguerabide

David E Kohne

Jeffrey T Jackson

Laurence Warden

Todd Peterson

Method for specific detection of one or more analytes in a sample. The method includes specifically associating any one or more analytes in the sample with a scattered-light detectable particle, illuminating any particle associated with the analytes with light under conditions which produce scattered light from the particle and in which light scattered from one or more particles can be detected by a human eye with less than 500 times magnification and without electronic amplification. The method also includes detecting the light scattered by any such particles under those conditions as a measure of the presence of the analytes.

Analyte assay using particulate labels

Methods for enhancing the dynamic range for specific detection of one or more analytes in assays using scattered-light detectable particle labels. The methods involve utilizing variations in detection technique and/or signal processing to extend the dynamic range to either or both of lower and higher concentrations.

Methods for providing extended dynamic range in analyte assays

The use of light scattering particles in the design, manufacturing, and quality control of microscale devices and process, and the analysis of solid substrate and porous substrate characteristics is described.

Use of light scattering particles in design, manufacture, and quality control of small volume instruments, devices, and processes

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La Jolla, CA, United States of America

Juan Yguerabide