The First Affiliated Hospital of Xi'an Jiao Tong University

Juan Wu

Huicong Du

Maoguo Shu

Renjianzhi Zhang

A preparation method of a magnetic hydrogel includes steps as follows. A gelatin solution, a sodium alginate solution, deionized water, and NdFeB particles are mixed thoroughly to obtain a reaction precursor A solution. Calcium carbonate, gluconolactone, transglutaminase, and deionized water are mixed thoroughly to obtain a reaction precursor B solution. The reaction precursor solution A is added into the reaction precursor solution B to stir thoroughly and mix to obtain a mixture, followed by sealing the mixture to place in a constant-temperature environment to obtain the magnetic hydrogel of GA-Al@NdFeB. The magnetic hydrogel of GA-Al@NdFeB is magnetized, thereby endowing the NdFeB particles embedded within the magnetic hydrogel of GA-Al@NdFeB with magnetic polarity to obtain a magnetized magnetic hydrogel of GA-Al@NdFeB. By using the magnetic hydrogels, mechanical loading of skin wounds can be achieved, wound contraction is promoted, and the purpose of wound repair is achieved.

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Xi'an, China

Juan Wu