Chinese Academy of Sciences

Tarapeutics Science Inc.

Hefei Cosource Pharmaceutical Co., Ltd.

Anqing Normal University

Juan Liu

Cheng Chen

Jing Liu

Li Wang

Qingsong Liu

Beilei Wang

Wenchao Wang

Chen Hu

Wei Wang

Aoli Wang

Xi Li

Hong Wu

Shuang Qi

Kailin Yu

Xixiang Li

Jiaxin Wu

Wen Chao Wang

Ao Li Wang

Feng Ming Zou

Bei Lei Wang

Wen Liang Wang

Qing Song Liu

Qing Wang Liu

Zheng Zhao

Yuanzhi Wang

Zizhen Shi

Xin Zheng

Zhong Huang

Zhouping Yin

Jiang Yan Cao

Xi Xiang Li

Provided is a novel PDGFR kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. Further provided are use and a method of the compound of formula (I) for preventing or treating conditions associated with PDGFR kinase activity, particularly use and a method for preventing or treating conditions associated with PDGFRα and/or PDGFRβ kinase activity.

Pyrazole derivatives and use thereof

The present invention belongs to the technical field of hard disk device, and specifically relates to a Hard Disk Device Based on Blockchain. The hard disk device comprises a storage unit and a protection unit; wherein a hard disk body stores information in the blockchain; the protection unit comprises a protective case, an airbag and an interface extension board; the airbag is laid flat on the inner bottom of the protective case; the interface extension board passes through a side wall of the protective case and is bolted to the protective case; a dust board in a first through hole of the interface extension board is located at the port on the interface extension board close to the hard disk body when the hard disk body is not placed in the protective case; the dust board is connected to the inside of the first through hole by a first spring.

Protective case for a hard disk device based on blockchain

Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases). 

Inhibitor of FLT3 kinase and use thereof

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Anhui, China

Juan Liu