The General Hospital Corporation

Aztherapies, Inc.

Juan B Gonzalez

David R Elmaleh

The present disclosure is directed to a composition comprising micronized cromolyn sodium, &#x3b1;-lactose, and a salt of fatty acid, wherein the &#x3b1;-lactose has a particle size distribution of Dof 45-70 &#x3bc;m, Dof 10-35 &#x3bc;m, and Dof 2-13 &#x3bc;m. The present disclosure is also directed to a method of treating Alzheimer's disease, amyloidosis-associated condition (AAC), traumatic brain injury, Huntington's disease, atherosclerosis, cytokine release syndrome (CRS), dementia, head injury, infection, neuroinflammation, prion disease, stroke, amyotrophic lateral sclerosis (ALS), Parkinson's disease, or asthma using the composition.

Powdered formulations of cromolyn sodium and alpha-lactose

The invention is directed to a composition comprising cromolyn sodium and ibuprofen, wherein the cromolyn sodium is micronized and the cromolyn sodium and ibuprofen are present in a weight ratio of 1:1-2. In one embodiment, the ibuprofen is passed through a sieve, such as a 300 &#x3bc;m sieve and to methods of making the same.

Growing community of inventors

Rochester, NH, United States of America

Juan B Gonzalez