Sk Biopharmaceuticals Co., Ltd.

Hyundai Motor Company

Korea Advanced Institute of Science and Technology

Lg Chem, Ltd

Kia Motors Corporation

Korea Research Institute of Chemical Technology

Legochem Biosciences, Inc.

Kia Corporation

Amkor Technology Singapore Holding Pte. Ltd.

Lg Life Sciences, Limited

K. C. Tech Co., Ltd.

Abl Bio Inc.

Ligachem Biosciences Inc.

Samsung Electronics Co., Ltd.

Tiumbio Co., Ltd.

Ju Young Lee

Ji Won Lee

Ji Yeon Kim

Chan Mi Joung

Yeo Jin Yoon

Jin Sung Kim

Myung Jin Jung

Yong Zu Kim

Ho Young Song

Jeiwook Chae

Dong Hoon Lee

Min Woo Jung

Yong Min Kim

Yeong Soo Oh

Chul-Woong Chung

Sun-Chang Kim

Dae Won Lee

Dong Uk Heo

Seung Hyun Lee

SAng Hyeon Kang

Choong Hoon Lee

Jungoh Huh

Boonjae Jang

Jun Ho Lee

Tae Yoon Park

Hyun Jung Lee

Sung Min Kim

Bong-Yong Lee

Won Bae Bang

Dong Joo Park

Bo Ram Lee

Jae Yun Kim

Sang Chul Lim

Seong Min Oak

Jin Young Khim

Juhee Kim

Bora Lee

Dong Ho Lee

Jae Won Lee

Jae-Sun Kim

Sun Chang Kim

JongChul Ye

Hun-Taek Kim

Shaun Bowers

Seong Mi Cho

Dong Chul Shin

Nam Ho Kim

Hyoung Rae Kim

Kwang Myung Cho

Eun Ju Choi

Nahm Ryune Cho

Young Koo Jang

Cheol Young Maeng

Jin Yong Chung

Yong Je Shin

Hye Kyung Min

Eun Ju Ryu

Hyo Jun Jung

Yong Soo Kim

Kyung Eun Park

Yu Jin Kim

Yu Jin Shin

Young Soon Kang

Jong Geon Jegal

Hyo Jung Choi

Je Ho Ryu

Su In Lee

Hyoungrae Kim

Yun-Hee Park

Jung Ha Lee

Jong Chul Ye

Yun Hee Park

Min Hwa Chang

Gi Tae Lim

Gyu Wan Han

Yoon Hwan Cho

Yangsoon Lee

Su Won Seol

Min Kyung Kim

Se Hwan Hong

Do Haeng Kim

Jeong Wook Mun

Bong Hyun Sung

Hyun Seok Lee

Chang Ki Kim

Jung A Lee

Jin Kyu Kang

Byungje Sung

Hoe Chul Jung

Ju Ahn Park

Myung Jea Choi

Keun-Ho Ryu

Byoung Su Kim

Donghoon Yeom

Dae Hyuck Kang

Kyungjin Park

Jinhyung Ahn

Chang Sun Lee

Byoung Woo Cho

The present invention relates to a pyrrolobenzodiazepine dimer prodrug and a ligand-linker conjugate compound thereof, a composition containing these, and therapeutic use thereof particularly as an anticancer drug. The stability of the compounds themselves and the stability thereof in plasma are excellent and the compounds are advantageous in terms of manifestation of toxicity, and thus the compounds are industrially useful in that it is possible to target proliferative diseases such as cancer, to perform a specific treatment, to maximize the drug efficacy, and to minimize the occurrence of side effects.

Pyrrolobenzodiazepine dimer prodrug and ligand-linker conjugate compound of the same

An anti-counterfeiting apparatus is capable of preventing delamination between layers laminated in an anti-counterfeiting device through a structural color expressed by a load and images formed by the structural color. The anti-counterfeiting apparatus may include a first layer formed of a flexible material and including a high-corrugation region and a low-corrugation region, a second layer formed on an upper portion of the high-corrugation region in a pattern, to be adhered to the first layer, and formed of a material having a Young's modulus greater than that of the first layer, and a third layer adhered to the first layer to cover the low-corrugation region and the second layer, and formed of a material having a Young's modulus greater than that of the first layer and a Young's modulus smaller than that of the second layer.

Forgery prevention apparatus to prevent delamination and forgery authentication method using the same

Disclosed is an electrode for a membrane-electrode assembly, in which a hydrophilic group and a hydrophobic portion of an ionomer are bonded to a catalyst so that the alignment of the hydrophilic group and the hydrophobic portion of the ionomer is controlled, and a method of manufacturing the same.

Electrode for a membrane-electrode assembly having improved water repellency and a method of manufacturing same

Disclosed are oxadiazole compounds and pharmaceutically acceptable salts thereof. The compounds and pharmaceutically acceptable salts thereof are specifically suitable for the treatment of neurological diseases such as epilepsy.

Compound having oxadiazole and pharmaceutical composition containing the same

The present specification relates to an organic light emitting device having high light emission efficiency. Such organic light emitting device comprises a light emitting layer provided between the cathode and the anode, and including an anthracene derivative represented by the following Chemical Formula 2, and an organic material layer provide between the cathode and the light emitting layer, and including a cyclic compound represented by the following Chemical Formula 1.  wherein Ar1, Ar2, X, G1, G2, m, n, R1-R8, Ar3, Ar4, L3, and I3 are described herein.

Organic light-emitting element

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same

Disclosed are an electrolyte membrane of a membrane-electrode assembly including an electronic insulation layer, which greatly improves the durability of the electrolyte membrane, and a method of preparing the same. The electrolyte membrane includes an ion exchange layer and an electronic insulation layer provided on the ion exchange layer, and the electronic insulation layer includes one or more catalyst complexes, and a second ionomer Particularly, each of the one or more catalyst complex includes a catalyst particle and a first ionomer coated on the entirety or a portion of the surface of the catalyst particle, and the one or more catalyst complexes are dispersed the second ionomer.

Electrolyte membrane of membrane-electrode assembly including electronic insulation layer and preparation method thereof

The present invention provides an organic light emitting device having improved driving voltage, efficiency and lifetime.

Organic light emitting device

The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically diseases associated with over-expression of ROR1, for example cancer. More specifically, the present invention relates to an antibody-drug conjugate comprising an antibody that binds to ROR1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.

Antibody-drug conjugate comprising antibody against human ROR1 and use for the same

The present disclosure relates to pyrrolobenzodiazepine dimer prodrugs and ligand-linker conjugates thereof. The present disclosure also relates to compositions and uses of said prodrugs and conjugates.

Disclosed is a temperature detection device. The device for detecting temperature of a processing liquid for substrate processing according to an embodiment includes a temperature measurement sensor installed adjacent to an outer surface of a tube through which the processing liquid flows, in which the temperature measurement sensor senses the temperature of the processing liquid in the tube.

Temperature detection device

In one example, a semiconductor device can comprise a substrate, a device stack, first and second internal interconnects, and an encapsulant. The substrate can comprise a first and second substrate sides opposite each other, a substrate outer sidewall between the first substrate side and the second substrate side, and a substrate inner sidewall defining a cavity between the first substrate side and the second substrate side. The device stack can be in the cavity and can comprise a first electronic device, and a second electronic device stacked on the first electronic device. The first internal interconnect can be coupled to the substrate and the device stack. The encapsulant can cover the substrate inner sidewall and the device stack and can fill the cavity. Other examples and related methods are disclosed herein.

Semiconductor devices and related methods

Provided are a recombinant yeast having improved ability to produce ginsenoside, which is prepared by overexpressing INO2 and INO4 or deleting OPT1 in a yeast having ability to produce ginsenoside, a method of preparing the yeast, and a method of producing ginsenoside by using the yeast.

Increased production of ginsenosides through yeast cell organelle improvement

Disclosed herein are a method and an apparatus for removing ghost artifacts of an echo planner image using a neural network. An image processing method according to an embodiment of the inventive concept includes receiving Fourier space data of an echo planar image, and restoring the echo planar image in which ghost artifacts are removed using a neural network. The receiving of the Fourier space data may include dividing the Fourier space data into the odd-numbered Fourier space data and even-numbered Fourier space data, and the restoring of the echo planar image may include obtaining the odd-numbered Fourier space data and even-numbered Fourier space data with the Fourier space interpolated using the neural network and restoring the echo planar image in which the ghost artifacts are removed based on the odd-numbered Fourier space data and even-numbered Fourier space data with the Fourier space interpolated.

Method for removing ghost artifact of echo planar imaging by using neural network and apparatus therefor

Growing community of inventors

Daejeon, South Korea

Ju Young Lee