Arzneimittelwerk Dresden Gmbh

Ju/ Rgen Liebscher

Gottfried Faust

Andreas Rolfs

Alexander Knoll

Peter Scharfenberg

Dieter Lohman

Aleksej Uschmajew

Eveline Morgenstern

The invention is directed to 3-aminopyrroles of formula I, which are largely new, to methods for the preparation and to their use as medicinal agents and preparations, as well as to anti-convulsive or analgesic preparations containing these 3-aminopyrroles. Disubstituted and monosubstituted amino groups are claimed as 3-amino substituents. The invention pursues the objective of developing largely new 3-aminopyrroles, which have CNS activity, particularly ones which anti-convulsive or analgesic properties, as well as methods for their preparation and their use as medicinal preparations. Pursuant to the invention, the synthesis is carried out by cyclizing open-chain precursors, such as aminoacrylic acid derivative, or by modifying pyrroles.

3-aminopyrroles, methods for their synthesis and for their

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Berlin, Germany

Ju/ Rgen Liebscher