Valneva Austria Gmbh

Valneva Se

Jürgen Wruss

Robert Schlegl

Michael Weber

Michael Möhlen

Karen Lingnau

Benjamin Wizel

Christoph Klade

Christoph Reinisch

Robert Seid

Karin Riedl

Ursula Schlosser

Ljubomir Paucz

Christian Ruiz

Mario Nebenführ

Jana Barbero Calzado

Mario NEBENFÜHR

Described herein are processes for purifying infectious Zika virus particles and uses of protamine in such processes.

Zika virus purification

The invention relates to means and methods for preparing aqueous composition comprising aluminum and a protein said composition comprising less than 700 ppm heavy metal on the basis of weight with respect to the aluminum content. The invention further relates to aqueous compositions comprising a protein and an aluminum-salt, said composition comprising less than 350 ppb heavy metal based on the weight of the aqueous composition.

Aluminum compounds for use in therapeutics and vaccines

The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein said composition comprising less than 700 ppm heavy metal on the basis of weight with respect to the aluminium content. The invention further relates to aqueous compositions comprising a protein and an aluminium-salt, said composition comprising less than 350 ppb heavy metal based on the weight of the aqueous composition.

The invention discloses pharmaceutical compositions in liquid form comprising a peptide with the amino acid sequence KLKLKLK and an oligodeoxynucleotide with the nucleic acid sequence (dIdC)and wherein the peptide and the oligodeoxynucleotide are present as sterile-filterable nanoparticles in the composition, thereby forming a suspension, characterized in that the mean particle size of the solid particles is less than 1 &#x3bc;m.

IC31 nanoparticles

1C31 nanoparticles

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Vienna, Austria

Jürgen Wruss