Richter Gedeon Vegyeszeti Gyar Rt

Jozsef Turley

Laszlo Szporny

Eva Palosi

Bela Kiss

Edit Toth

Erzsebet Lapis

Istvan Laszlovszky

Istvan Hajdu

Dora Groo

The invention relates to novel 1,4-disubstituted piperazine derivatives of the general formula (I), pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) ##STR1## R.sub.1 and R.sub.2 are the same or different and stand for hydrogen or halogen or a lower alkyl, trihalomethyl or lower alkoxy group. The compounds of the general formula (I) are therapeutically useful for the treatment of diseases arising from a hypofunction of the dopaminergic system.

1,4-disubstituted piperazines, pharmaceutical compositions thereof and

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Budapest, Hungary

Jozsef Turley