Ion Beam Applications S.a.

Jozef Comor

Jean-Michel Geets

Yves Jongen

Bernard Lambert

Benoît Nactergal

Michel Guyette

Djuro Jovanovic

Gerd-Jürgen Beyer

The embodiments of the present disclosure provide a method for producing Ac-225 from Ra-226, comprising submitting Ra-226 to a photo-nuclear process, collecting an electrochemical precipitation of an Ac-225 on a cathode in a recipient, removing the cathode from the recipient after the electrochemical precipitation of the Ac-225, transferring the cathode to a hot cell environment, and extracting the Ac-225 from the cathode in the hot cell environment. The Ra-226 may comprise a liquid solution in the recipient, and submitting Ra-226 to the photo-nuclear process may comprise irradiating the Ra-226 to produce Ra-225. The Ra-225 may decay into Ac-225 upon irradiation of the Ra-226.

Method for producing Ac-225 from Ra-226

A capsule for the transfer of a target material in a conveying system between a target irradiation station and a collecting station comprising: a beamline channel for the passage of an energetic beam irradiating the target material, a target holder holding the target material or a substrate backing the target material at a glancing angle with respect to the beamline channel axis, a degrader foil positioned across the beamline channel for degrading an energy of the energetic beam upstream of the target material, a target cooling inlet and a target cooling outlet for passage of a cooling fluid in a target cooling duct in a vicinity of the target holder such that the target material can be cooled during an irradiation, and a degrader foil cooling inlet and a degrader foil cooling outlet for passage of a cooling gas in a vicinity of the degrader foil.

System for the irradiation of a target material

The present disclosure relates to an apparatus for the synthesis of chemical compounds, e.g., radiopharmaceutical compounds. In one implementation, the apparatus may include a synthesis module and a loading module configured to receive multiple chemical cassettes having reagents and a transfer mechanism. The apparatus may further include a shifter configured to move the cassettes from a location on the loading module to a location connected to the synthesis module on an interface configured to connect to the cassette.

Apparatus for the synthesis of radiopharmaceutical products

The present invention relates to an apparatus for producing a radioisotope by irradiating a target fluid comprising a precursor of said radioisotope with a particle beam produced by a particle accelerator, the apparatus comprising: &#x2014;a housing comprising a target cavity for receiving said target fluid, said housing having an opening for allowing the passage of the said particle beam into the said cavity; &#x2014;a dual foil flange for closing said opening of the target cavity, said dual foil flange comprising: &#x2014;a standoff comprising a central hole; &#x2014;a first and a second foil able to allow the passage of the said particle beam and located respectively on a first side and a second side of the said standoff, covering the said central hole and forming a cooling cavity; &#x2014;a first flange and a second flange for sealing respectively the said first and second foil on said standoff; &#x2014;at least an inlet channel and at least an outlet channel, for flowing a cooling fluid through the cavity of the dual foil flange; &#x2014;guiding means for positioning said dual foil flange in an in-line position in which a said foil is facing said opening of said housing.

Apparatus for producing a radioisotope comprising means for maintenance and method of maintenance for said apparatus

The present invention is related to a device and a method for producing a radioisotope of interest from a target fluid irradiated with a beam of accelerated charged particles, the device includes in a circulation circuit (): an irradiation cell () having a metallic insert () able to form a cavity () designed to house the target fluid and closed by an irradiation window (), the cavity () including at least one inlet () and at least one outlet (); a pump () for circulating the target fluid inside the circulation circuit (); an external heat exchanger (); the pump () and the external heat exchanger () forming external cooling means of the target fluid; the device means for pressurizing () of the circulation circuit () and the external cooling means of the target fluid are arranged in such a way that the target fluid remains inside the cavity () essentially in the liquid state during the irradiation.

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Belgrade, Republic of Serbia

Jozef Comor