Alza Corporation

Joyce C Anthony

Jeffrey Wayne Etter

Vincent Joseph Ferrari

James Horvath

Liang C Dong

Patrick S-l Wong

Susan M Marks

Patrick S -l Wong

Christopher M Ohms

Christopher M G Ohms

Radomir N Vukadin

Radomir N M Vukadin

Danusia Szumowski

The present invention is directed to a closure system for an oral active agent delivery device. The device comprises an elongate tubular member having first and second ends. The closure system includes a deformable closure means adapted to allow delivery of the active agent upon deformation. The closure system prevents spillage and maintains the integrity of the dose within the device. In use, the closure system is deformed and separated from the second end of the tubular member, liquid is drawn up into the first end of the member, and the liquid and active agent are drawn out of the second end of the member and into the patient's mouth.

Closure system for an active agent delivert device

Closure system for an active agent delivery device

A method is described for delivering a beneficial agent, such as an antiinflammatory agent, to the site of a painful condition in the oral cavity of a human being that utilizes an oral dosage form having an immediately releasable topical anesthetic and a sustained release beneficial agent. The topical anesthetic is released substantially independently of the beneficial agent to provide immediate pain relief and the application of the beneficial agent is continued over a long period of time.

Oral dosage and method for treating painful conditions of the oral cavity

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Woodside, CA, United States of America

Joyce C Anthony