Takeda Chemical Industries, Inc.

Nippon Seisen Co., Ltd.

Jotaro Kishimoto

Nobuo Tanaka

Seiji Ohtani

Kotaro Wakamatsu

Takayuki Hagihara

Yukihide Noguchi

Shuji Morimoto

Hideomi Ishibe

Haruhiko Yoshida

Masakazu Oi

Seiji Chtani

Takeshi Nishimura

Yoshio Nishida

Norio Shirai

Kiyoshi Nagai

A prefilled syringe capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition axially slidable in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole divides the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.

Prefilled syringe

A prefilled syringe capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition slidable axially in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole dividing the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.

A prefilled syringe is capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition axially slidable in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole divides the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.

A filling machine provided with a filling amount weighing apparatus which is used in a step of preparing medical supplies and so on, and continuously fills automatically powder, liquid or the like of a very small amount into a container such as vial, ampul or the like so as to weigh the filling amount, on the employment of an electronic balance to effect a weighing operation of high speed and precision so as to improve the filling amount accuracy through the reduction in dispersion in the filling amount.

Filling apparatus

A powder-air separator with a filter made by sintering short-cut filament-shaped particles or by sintering a mixture of short-cut filament-shaped particles and ordinary atomized round particles.

Powder-air separator for use in a powder filling apparatus

An automatic closure cleansing machine has at least two rotary carriers each having a plurality of receptacles arranged in equally spaced relation to each other and also in equally spaced relation to the axis of rotation of the corresponding rotary carrier, and first and second cleansing liquid applicators being positioned adjacent the rotary carriers, respectively, for spraying a cleansing liquid under pressure towards the closure members carried by the rotary carrier by the effect of a suction force. For this purpose, the receptacles on each rotary carrier are successively communicated to a source of vacuum. One of the opposed sides of each of the closure members is cleansed during the transportation of the closure member by the first rotary carrier while the other of the opposed sides of the closure member is cleansed during the transportation of the closure member by the second rotary carrier. A silicone resin coating may be applied to the closure members after they are removed from the second rotary carrier.

Growing community of inventors

Nishinomiya, Japan

Jotaro Kishimoto