Quantum Design, Inc.

Quantum Design International, Inc.

Consejo Superior De Investigaciones Cientificas

University of Zaragoza

Jost Diederichs

Michael Bancroft Simmonds

Randall Black

Kurt Gordon Jensen

Andreas Amann

Ronald E Sager

William Neils

Dinesh Martien

Conrado Rillo Millan

Ronald Sager

A method and device for purifying a process gas mixture, such as a cryogen gas, in which impurity components of the mixture are removed by de-sublimation via cryo-condensation. The gas mixture is cooled to a temperature well below the condensation temperature of the impurities, by direct exchange of the gas mixture with a cooling source disposed in a first region of the device. The de-sublimated or frozen impurities collect about the cooling region surfaces, and ultimately transferred to a portion of the device defining an impurities storage region. The output-purified gas is transferred from the impurities storage region, is optionally passed through a first micrometer sized filter, through a counter-flow heat exchanger, and ultimately up to an output port at room temperature. A method of purging the collected impurities and regenerating the device is also disclosed.

Apparatus and method for purifying gases and method of regenerating the same

A cryocooler-based gas scrubber, or cryocooler-based gas purifier, utilizes the cooling power of a cryocooler to cool and condense cryogen gas forming coalesced impurities which are then filtered through a filter matrix, such as for example a fiberglass filter matrix. The scrubber may further comprise a counter-flow heat exchanger for warming the purified gas prior to dispensing at an outlet for storage or consumption.

Cryocooler-based gas scrubber

A liquefier includes a Dewar having a storage portion and a neck portion extending therefrom. A hermetically isolated liquefaction chamber is disposed within the neck of the Dewar. One or more control components including a temperature and pressure sensor are coupled to a CPU and disposed within the liquefaction chamber for dynamic control of liquefaction conditions. A gas flow control is coupled to the CPU for regulating an input gas flow into the liquefaction chamber. A volume surrounding the liquefaction chamber may be adapted to provide a counter-flow heat exchange. These and other features provide improved liquefaction efficiency among other benefits.

Liquefier with pressure-controlled liquefaction chamber

A modular architecture for helium compressors is described. In the modular architecture, oil is cooled independently from gas. In one aspect, the oil is cooled subsequent to the gas with a series of water-cooled heat exchangers. In another aspect, the oil is cooled using a water-cooled heat exchanger coupled to a radiator, and the gas is independently cooled using a refrigerant-cooled heat exchanger coupled to a condensing unit.

Modular architecture for helium compressors

A cryostat for providing temperature regulation, one purpose being measuring physical properties of materials, the cryostat employing a superconducting magnet assembly for generating variable magnetic field in the sample space and a cryogenic cooler for cooling the sample space. The cryogenic cooler chamber configuration provides for efficient heat exchange between different stages of the cryogenic cooler without the need for physical heat links. This construction enables selective delivery of cooling power from the cryogenic cooler to the desired areas within the cryostat without using flexible physical thermal links. A counter flow exchanger and ambient temperature valves facilitate efficient use of the cryogenic cooler stages. The removal of large heat load generated by the superconducting magnet while operating in the sweeping mode is achieved, in part, by employing a solid plate thermal coupling element between the cryogenic cooler chamber and the magnet assembly.

Method and apparatus for controlling temperature in a cryocooled cryostat  using static and moving gas

A magnet system for generating a magnetic field may include a superconducting magnet, a switch, and a heater element thermally coupled to the switch. The superconducting magnet is structured to generate magnetic fields, and the switch includes a non-inductive superconducting current carrying path connected in parallel to the superconducting magnet. In general, the switch is structured to only carry a level of current that is a portion of the current required to obtain a full field by the superconducting magnet.

Superconducting quick switch

An apparatus is provided for quantitatively measuring samples whose amount or other characteristic quality is to be determined. The samples are arranged in a predefined pattern and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one substantially flat sensor such as sensing coils fabricated in a gradiometer configuration.

Method and apparatus for making measurements of accumulations of magnetically susceptible particles combined with analytes

An apparatus is provided for quantitatively determining amounts and identities of substances whithin patterns of magnetic particles, such as within lateral flow membranes, microfludic systems, and the like. Magnetic particles are complexed with substances to be determined and are excited in an oscillating magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.

Method and apparatus for making measurements of patterns of magnetic particles in lateral flow membranes and microfluidic systems

Apparatus for detection and measurement of agglutinations of magnetic particles employing Hall sensors. A low frequency AC signal is employed to excite or bias the Hall sensors which reside in a DC magnetic field. The particles are moved into operative relationship with the Hall sensors in order to generate a signal representing the number of particles on the substrate. The method for such detection and measurement is also part of the invention.

Method and apparatus for quantitative determination of accumulations of magnetic particles

An apparatus is provided for quantitatively measuring groups of magnetic particles. The particles are complexed with substances to be determined and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.

Computer program for making measurements of accumulations of magnetic particles

An apparatus is provided for quantitatively measuring combinations of magnetic particles combined with analytes whose amount or other characteristic quality is to be determined. The magnetic particles are complexed with the analytes to be determined and are excited in a magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency in the manner of a dipole to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.

Growing community of inventors

Poway, CA, United States of America

Jost Diederichs