Siemens Healthcare Diagnostics Gmbh

Dade Behring Inc.

Joson K Joseph

Frank Krufka

Bestin Abraham

Arnold Lloyd Lewis

Tan Bui

A computer-implemented method for calibrating a photometer in an in-vitro diagnostics analyzer includes generating a cuvette map of a reaction ring identifying a plurality of cuvette locations. The cuvette map is used to identify a plurality of reference measurement areas between the plurality of cuvette locations. A plurality of reference measurements are acquired in the reference measurement areas using the photometer. The photometer is automatically calibrated based on a comparison of the reference measurements to a predetermined standard setup of the photometer.

Eliminating source lamp intensity drift effect using reference measurement between cuvettes

A computer-implemented method for performing photometric cuvette mapping includes detecting edges associated with a plurality of gaps between a plurality of vessels in a reaction ring during a complete rotation of a reaction ring. Each gap is determined according to an edge detection process which includes identifying: a vessel interior in response to detection of a first predetermined number of photometer device control manager (DCM) measurements below a threshold value; a rising edge in response to detection of a second predetermined number of photometer DCM measurements above the threshold value; and identifying a falling edge in response to detection of a third predetermined number of photometer DCM measurements below the threshold value. The edge detection process further includes recording the rising edge and the falling edge as being indicative of one of the plurality of gaps.

Photometric cuvette mapping

A liquid level sensor confirms actual physical contact between a probe and a liquid by verifying that any change in capacitance of the sensor is constant over a given time period and thereby is not caused by spurious electrical disturbances or other measuring irregularities.

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Bear, DE, United States of America

Joson K Joseph