Abbott Cardiovascular Systems, Inc.

Joshua Smith

Mikael Trollsas

Michael H Ngo

Syed F Hossainy

John E Papp

Hung T Nguyen

Dudley Shelton Jayasinghe

Yongjin Xie

Gregory Orr

Yu-Chun Ku

Ron Farnbach

John Joseph Stankus

Dariush Davalian

James Su

Erik David Eli

Shadid Askar

Dudley Jayasinghe

Gregory C Orr

Methods for making scaffolds for delivery via a balloon catheter are described. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold structure has patterns that include an asymmetric or symmetric closed cell, and links connecting such closed cells.

Processes for making crush recoverable polymer scaffolds

A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.

Polymer scaffolds for peripheral vessels

Formulations and methods are disclosed which provide controlled, sustained release of a biologic therapeutic to a space within the body. More specifically, formulations comprising a plurality of hydrophilic polymer strands, and methods of forming and administering such formulations, are disclosed. In some embodiments, the formulations exhibit a burst release, an initial release, a triphasic release, and release over thirty to ninety days of the biologic therapeutic. In some embodiments, the formulations exhibit reversible precipitation of the biologic therapeutic into precipitates having a diameter of about 50 nm to about 10 &#x3bc;m.

Delivery of biologic therapeutics

Growing community of inventors

Campbell, CA, United States of America

Joshua Smith