Hewlett-packard Development Company, L.p.

Joshua M Yu

Manish Giri

Matthew David Smith

Jeffrey Allen Nielsen

Chantelle Domingue

Kevin Francis Peters

Christie Dudenhoefer

Kenneth Ward

Hilary Ely

Tod Woodford

George H Corrigan

Greg Scott Long

Sriram Ramamoorthi

Paul Joseph Bruinsma

Diane R Hammerstad

Jeremy Harlan Donaldson

Chris Bakker

Jeremy Sells

Angela White Bakkom

Sadiq Bengali

Melinda M Valencia

Sirena Chi Lu

Masoud K Zavarehi

Vincent Thomas Remcho

Christopher Hans Bakker

Mark Sanders Taylor

David H Ochs

Rachel M White

Vignesh Kannan

Kenneth Joseph Duda

Mark David Johnson

Shameed Sait M A

Sadiq Bengall

Sadig Bengali

Masoud Zavarehi

Chantelle E Domingue

George H Corrigan Iii

Giri Manish

Jeffrey A Neilsen

In one example in accordance with the present disclosure, a system is described. The system includes a fluidic die to advance across an ejection path relative to a substrate. The fluidic die includes a channel to contain a portion of a sample fluid, a sensor to detect passage of a particle within the sample fluid into the channel, and an ejection device. The ejection device is to eject the particle. The system also includes a controller. The controller identifies discrete locations along the ejection path as waste sites as the fluidic die advances along the ejection path. This is done by 1) classifying the particle as a target particle or a non-target particle, 2) upon identification of a target particle, ejecting the target particle to a target site of the substrate, and 3) upon identification of a non-target particle, ejecting the non-target particle to a waste site.

Identifying substrate waste sites

Integrated circuit

A system may comprise a voltage upconverter, a universal serial bus (USB) connector to receive an input voltage from a USB port on a computing device, and a microfluidic diagnostic chip communication link to electrically couple the voltage upconverter to a microfluidic diagnostic chip wherein the voltage upconverter is to convert the input voltage to be received by the USB connector to an output voltage sufficient to drive a pump on the microfluidic diagnostic chip. A diagnostic system may comprise a microfluidic diagnostic chip comprising a pump and a voltage upconverter to receive an input voltage from a universal serial bus (USB) port of a computing device and to convert the input voltage into an output voltage that powers activation of the pump.

Voltage upconverter

According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.

Microfluidic apparatuses

The present disclosure is drawn to microfluidic chips. The microfluidic chips can include an inflexible material having an elastic modulus of 0.1 gigapascals (GPa) to 450 GPa. A microfluidic channel can be formed within the inflexible material and can connect an inlet and an outlet. A working electrode can be associated with the microfluidic channel and can have a surface area of 1 &#x3bc;mto 60,000 &#x3bc;mwithin the microfluidic channel. A bubble support structure can also be formed within the microfluidic channel such that the working electrode is positioned to electrolytically generate a bubble that becomes associated with the bubble support structure.

Microfluidic chips

According to an example, a microfluidic apparatus may include a fluid slot and a foyer that is in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer. The microfluidic apparatus may also include an electrical sensor to measure a change in an electrical field caused by a particle of interest in a fluid passing through the channel from the fluid slot to the foyer, an actuator to apply pressure onto fluid contained in the foyer, and a controller to receive the measured change in the electrical field from the electrical sensor, determine, from the received change in the electrical field, an electrical signature of the particle of interest, and control the actuator to control movement of the particle of interest based upon the determined electrical signature of the particle of interest.

Microfluidic apparatuses for fluid movement control

According to an example, a microfluidic apparatus may include a fluid slot, a foyer in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer, a sensor to detect a presence of a particle of interest in a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to receive information from the sensor, determine, from the received information, whether a particle of interest has passed through the channel, and control the actuator to expel fluid in the foyer through the nozzle based upon the determination.

Systems, methods, and computer readable medium to provide patterned layer deposition of liquid types to a plate surface in layers organized in layouts with sites of patterns aligned to a plate origin of the plate surface. At least one layer includes a layout defining a geometric layout of the plate surface.

Patterned layer deposition

Example implementations relate to a microfluidics sensing system. For example, a microfluidics sensing system may include a portable computing device to execute a microfluidics application, a microfluidic chip coupled to the portable computing device, the microfluidic chip including a microfluidic pumping and sensing region to perform a test on a biologic sample, and a printed circuit board (PCB) on a microfluidic reader to instruct the microfluidic pumping and sensing region to perform the test based on a command received from the microfluidics application.

Microfluidics sensing system

Embodiments of a fluid delivery system are disclosed.

Fluid delivery system

A fluid-ejection printhead die includes a fluid-ejection firing element and an electrochemical cell. The fluid-ejection firing element is to cause droplets of fluid to be ejected from the fluid-ejection printhead die. The electrochemical cell is to measure an electrical property of the fluid. The fluid-ejection firing element and the electrochemical cell are both part of the fluid-ejection printhead die.

Fluid-ejection printhead die having an electrochemical cell

A method and an apparatus for dispensing liquid are disclosed. The method includes the steps of storing one or more liquids in a thermal inkjet print head and providing a well plate having at least one well. At least one of the liquids is dispensed from the thermal inkjet print head into at least one well. The volume of the dispensed liquid is a fraction of the total required volume of the liquid in the at least one well, and the dispensing step is performed multiple times to dispense the required volume of the at least one liquid in at least one well.

Method and system for dispensing liquid

Embodiments of a fluid transfer device are disclosed.

Fluid transfer device including a die

A system for sensing a property of a fluid comprises a fluid channel operable to receive the fluid therein, a flexible arm having a free end positioned within at least a portion of the fluid channel, a fluid actuator disposed sufficiently close to the flexible arm such that actuation of the fluid actuator induces movement of the flexible arm when the fluid is present, and a deflection sensing system operable to quantifiably detect movement of the flexible arm.

Cantilevers for sensing fluid properties

Growing community of inventors

Corvallis, OR, United States of America

Joshua M Yu