Cardica, Inc.

Joshua M O Newth

Bryan Dale Knodel

Philipe Roget Manoux

James T Nielsen

Nathan H White

David L Bombard

Bernard A Hausen

Theodore M Bender

A method of performing anastomosis between a graft vessel and a target vessel, each having a circumferential wall and a lumen therethrough, may include providing an anastomosis tool including a tissue effector and a fluid-driven actuator operationally connected to that tissue effector; connecting the fluid-driven actuator to an energy source; placing an end of the graft vessel in proximity to the side of the target vessel; and actuating the fluid-driven actuator to connect the end of the graft vessel to the side of the target vessel.

Anastomosis method utilizing tool with fluid-driven actuator

A method for closing a patent foramen ovale in the heart tissue of a patient may include percutaneously advancing a connector applicator to the patent foramen ovale, registering the connector applicator with the patent foramen ovale, deploying connectors into heart tissue to close the patent foramen ovale; and percutaneously removing the connector applicator from the heart. One or more anchors may be used to register the connector applicator with the patent foramen ovale. The connector applicator may include a driver having a longitudinal passage therein, where at least part of at least one connector is positioned within the passage.

Apparatus and method for closure of patent foramen ovale

An anastomosis tool may include a tissue effector having an anvil and a staple holder movable relative to one another, where that tissue effector may be movable from an open position to a closed position. A fluid-driven actuator may be utilized to move the tissue effector between those positions, and/or to deploy connectors from the staple holder when the tissue effector is in the closed position. The fluid-driven actuator may utilize pressurized gas stored in a cylinder or reservoir within the anastomosis tool. A separate clip applier may be used to close the entry hole made by the anvil in a target vessel.

Anastomosis tool actuated with stored energy

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Palo Alto, CA, United States of America

Joshua M O Newth