Trust-biosonics, Inc.

Joshua L Rychak

Alice Luong

Shih-Tsung Kang

ChungHsin Wang

A method for ascertaining the presence of target-bound microbubbles in the context of ultrasound molecular imaging is taught. This method, referred to herein as dynamic scaling ultrasound molecular imaging, relies upon the time-varying behavior contrast agents within a region expressing a molecular imaging target and that within a reference region. Ultrasound contrast agents compositions that enable use of the method are also taught. The method is useful for the use of ultrasound molecular imaging in diagnosing and monitoring treatment.

Composition and methods for sensitive molecular analysis

Compositions and methods for molecular imaging of selectins are disclosed. Specifically, compositions comprising medical imaging contrast-producing agents associated with the extracellular domain of TIM-1 as a targeting ligand for use in molecular imaging of selectins are disclosed. Also, methods of using the extracellular domain of TIM-1 as a ligand for achieving specific targeting to selectins as therapeutic drug delivery vehicles is also disclosed.

Growing community of inventors

Oceanside, CA, United States of America

Joshua L Rychak