The General Hospital Corporation

Massachusetts General Hospital Corporation

Metabolon, Inc.

Siegel, Corey a.

Knuth, Douglas

Joshua Korzenik

Corey A Siegel

Douglas Knuth

Jeffrey R Shuster

Danny Alexander

Garrett Zella

Described are kits, food compositions and methods for cleaning the bowel, e.g., in preparation for a medical procedure, e.g., a diagnostic or treatment procedure, such as an endoscopic or surgical procedure, or radiologic imaging such as CT colography.

Methods and compositions for bowel cleansing before a medical procedure

The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of inflammatory bowel disease, methods for distinguishing between inflammatory bowel diseases, methods of determining predisposition to inflammatory bowel disease, methods of monitoring progression/regression of inflammatory bowel disease, methods of assessing efficacy of compositions for treating inflammatory bowel disease, methods of screening compositions for activity in modulating biomarkers of inflammatory bowel disease, methods of treating inflammatory bowel disease, as well as other methods based on biomarkers of inflammatory bowel disease.

Metabolite biomarkers to distinguish Crohn's disease from ulcerative colitis and methods using the same

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Dover, MA, United States of America

Joshua Korzenik