Reconstructive Technologies, Inc.

Marz Medical, Inc.

Other

Joshua Korman

Antony Jonathan Fields

Alexander Kazaks

Gary B Greenburg

Tissue expansion system includes a pump, a controller, and inflatable bladder, and a pressure sensor. The pump is adapted for substantially continuous operation in response to a pressure within a subcutaneously implanted inflatable bladder. The pump is thus able to deliver inflation medium to the bladder when the pressure within the bladder is below a predetermined lower threshold while stopping delivery of the fluid when the pressure rises above a higher threshold or reaches a predetermined maximum volume.

Method and system for in situ tissue expansion

A tissue expansion system includes driver assembly having a syringe pump and a controller held in a common enclosure. The driver assembly is connected to both an inflatable bladder and an inflation medium source. Fluid is delivered from the driver assembly to the inflatable bladder through a pressure sensor. The pump is actuated to deliver predetermined incremental volumes of the inflation medium to the inflatable bladder at spaced apart time intervals. Pressure is monitored and the pumping is interrupted if the pressure exceeds a predetermined high threshold value. Pumping is recommenced when the pressure falls below a lower threshold value until the total incremental delivery volume has been reached.

Method and system for programmed in situ tissue expansion

An apparatus for increasing the rate of expansion of tissue area and volume, either in vivo or in vitro, which comprises a tissue expansion device suitable for expansion of tissue and a controller connected to the device, wherein the controller causes the device to subject the tissue to stretching forces that alternatively increase and decrease to provide a series of stretch and relax phases during a period of tissue expansion without intervention of an operator.

Apparatus for tissue expansion using pulsatile motion

A method of increasing the rate of expansion of tissue area and volume, either in vivo or in vitro, which comprises preparing a tissue for expansion and subjecting the tissue to stretching forces, wherein the stretching forces are alternatively increased and decreased to provide alternating periods of stretch and relax cycles.

Method for tissue expansion using pulsatile motion

A method of growing complete vertebrate skin in vitro, which comprises obtaining a segment of vertebrate skin, positioning the skin segment in an artificial cell-growth medium containing sufficient nutrients to maintain growth of cells of the skin, and subjecting the skin segment to stretching forces while the skin segment is in the medium. Skin produced by the method and an apparatus for carrying out the method are also part of the present invention.

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Los Altos Hills, CA, United States of America

Joshua Korman