Imperial College Innovations Limited

Cambridge Enterprise Limited

Imperial Innovations Limited

Joshua Benno Edel

Anthony Edward George Cass

Florian Hollfelder

Aleksandar Ivanov

Kevin Joseph Freedman

Jasmine Y Y Sze

Binoy Paulose Nadappuram

Paolo Cadinu

Ren Ren

Aleksandar Petrov Ivanov

Fabrice Matthieu Gielen

Andrew James Demello

Liisa Darnell Van Vliet

Sean Richard Anthony Devenish

Xize Niu

The disclosure relates to a dielectrophoretic tweezer, and associated methods of fabrication and use. The tweezer comprises a first end and a second end, in which the first end has a lateral dimension of less than 10 microns; a structure, extending in a longitudinal direction between the first and second ends, comprising an electrically insulating barrier defining a first chamber and a second chamber within the structure, in which the first and second chambers are insulated from each other by the electrically insulating barrier; a first electrode in the first chamber at the first end; and a second electrode in the second chamber at the first end, in which a width of the electrically insulating barrier separating the first electrode from the second electrode is 50 nm or less.

Dielectrophoretic tweezer

The disclosure relates to an apparatus and associated method for concentration of polarizable molecules within a fluid medium. The apparatus comprising a structure defining a cavity, having a cross-sectional dimension of 200 nm or less; at least two translocation electrodes positioned relative to the structure to enable generation of a DC electric field passing through the cavity; and at least two trapping electrodes positioned relative to the structure to enable generation of a time-varying electric field proximal to the cavity inlet.

Apparatus and method for concentration of polarizable molecules within a fluid medium

THE present application relates to a method of detecting one or more analytes in a sample, the method comprising (a) providing a carrier nucleic acid molecule with at least one single-stranded region; (b) providing one or more aptamers specific for the analyte, wherein the aptamers additionally comprise a single-stranded portion complementary to at least one single-stranded region on the carrier nucleic acid; (c) contacting the carrier nucleic acid and one or more aptamers with the sample, forming a carrier nucleic acid/N aptamer/analyte complex, and; (d) detecting the presence of the carrier nucleic acid/aptamer/analyte complex.

Analyte detection method

Growing community of inventors

London, United Kingdom

Joshua Benno Edel