Array Biopharma Inc.

Genentech, Inc.

Josh Hansen

Joseph P Lyssikatos

Ellen Ruth Laird

George T Topalov

Brad Newhouse

Jonas Grina

Mike Welch

Alan G Olivero

Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. 

Imidazopyrazines as Raf inhibitor compounds

Pyrazolyl compounds of Formulas Ia and Ib are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using pyrazolyl compounds for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. 

RAF inhibitor compounds and methods

Growing community of inventors

Longmont, CO, United States of America

Josh Hansen