Cerevasc, LLC

Avava, Inc.

The General Hospital Corporation

Zeltiq Aesthetics, Inc.

Tenzin LLC

Foster-miller, Inc.

Neograft Technologies, Inc.

Xeltis Ag

Blossom Innovations, LLC

Blossoms Innovations, LLC

Joseph Ting

R Rox Anderson

Dieter Manstein

J Christopher Flaherty

Joseph M Gordon

Andrew Ziegler

Timothy Robinson

David A Rezac

Adel M Malek

Carl Heilman

Jayant D Bhawalkar

Charles Holland Dresser

Stephen C Evans

Paul Andrew Glazer

Lorenzo Soletti

Jon McGrath

David Ray

William A Farinelli

Amos G Cruz

Richard Stephen Wisdom

Mohammed S El-Kurdi

Liem Vu

Shane Siwinski

Jerry Brightbill

Henry Hin Lee Chan

Samuel W Tolkoff

Brian P Farrell

Vincent Zuo

Gregory T Martin

Lilit Garibyan

Richard Rox Anderson

Ayan A Bhandari

Timothy W Robinson

Joseph Gordon

Kachiu Lee

Oge Onwudiwe

Irina Erenburg

Jeremy Bowman

Jennet Toyjanova

Jonathan B O'Keefe

Henry H L Chan

Henry Hl Chan

Jeffrey C Cerier

Jonathan B O'KEEFE

Thomas R Johnson

Brian Farrell

Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour.

Methods and systems for draining cerebrospinal fluid into the venous system

A cooling element includes a frame including one or more datums. The cooling element also includes a first window including a first proximal surface and a first distal surface. The first window is sealed to the frame. The cooling element further includes a second window sealed to the frame. The second window includes a second proximal surface and a second distal surface. The second window is configured to contact a target tissue or a tissue adjacent to the target tissue via the second distal surface. The cooing element also includes a coolant chamber located between the first distal surface of the first window and the second proximal surface of the second window and configured to receive a coolant. The first window, the second window and the coolant chamber are configured to receive and electromagnetic radiation (EMR), and transmit a portion of the received EMR to the target tissue.

System and method for tissue treatment

A method includes depositing a plurality of dopant particles within a predetermined region of a transparent material. The method also includes focusing a laser beam along an optical axis to a focal region that overlaps with at least a portion of the predetermined region. The focal region can irradiate at least a first dopant particle of the plurality of dopant particles. The method further includes adjusting a parameter of the laser beam to generate a plasma configured to form an inclusion within the transparent material. The method additionally includes scanning the focal region along a path within the transparent material to elongate the inclusion generally along the path.

Apparatus for materials processing

Cosmetic method and apparatus are provided that can provide cooling and/or freezing of skin tissue proximal to the skin surface to generate an appearance of lightening or reduced pigmentation in the skin. The skin can be cooled to a temperature of less than about &#x2212;5 degrees Celsius for a duration of about one minute or less, using a cooled surface that is at least 3 cm in width. A cooling arrangement can be provided to provide controlled heat removal from the skin tissue being treated. A sensor can optionally be provided to detect freezing of tissue proximal to the cooled surface.

Method and apparatus for cryogenic treatment of skin tissue

A method includes depositing within a predetermined region of a target tissue with a plurality of dopant particles. The method also includes focusing a laser beam to a focal region that overlaps with at least a portion of the predetermined region. The focal region includes at least a first dopant particle of the plurality of dopant particles. The method further includes adjusting a first parameter of the laser beam to generate plasma within a plasma volume comprising the first dopant particle.

Apparatus for selective treatment of tissue

A treatment system can include a channel generation system configured to expose an infected region of a target tissue with a laser beam traveling along an optical axis and focused at a focal volume located in or adjacent to the target tissue. The laser beam can have a wavelength ranging from about 100 nm to about 400 nm. The laser beam can be configured to generate at least a first channel in the infected region. The treatment system can also include a detection system configured to detect a first radiation generated by one or more of (i) the target tissue, (ii) a fungi coupled to the infected region in the target tissue, and (iii) an adjacent tissue located proximal to the target tissue as a result of interaction with the laser beam. The treatment system can also include a delivery system configured to deposit an active treatment agent in the at least first channel.

Therapeutic laser system and method

Cosmetic method and apparatus are provided that can provide cooling and/or freezing of skin tissue proximal to the skin surface to generate an appearance of lightening or reduced pigmentation in the skin. The skin can be cooled to a temperature of less than about &#x2212;5 degrees Celsius for a duration of about one minute or less, using a plurality of cooled contact surfaces, each having a width between about 2 mm and about 20 mm. A cooling arrangement can be provided to provide controlled heat removal from the skin tissue being treated. A sensor can optionally be provided to detect freezing of tissue proximal to the cooled surfaces.

An electromagnetic beam scanning system and corresponding method of use is provided. The system includes a motor, a reciprocating mechanism, and a focus optic. The motor is configured to generate a rotational movement. The reciprocating mechanism is operatively coupled with the motor and configured to convert the rotational movement to a reciprocating movement including a plurality of strokes along a first scanned axis. The reciprocating movement has a constant speed over a portion of at least one stroke of the plurality of strokes. The focus optic is operatively coupled to the reciprocating mechanism such that the focus optic moves experiences the reciprocating movement of the reciprocating mechanism. The focus optic is configured to focus an electromagnetic radiation (EMR) beam incident upon the focus optic to a focus along an optical axis substantially orthogonal to the first scanned axis.

Electromagnetic radiation beam scanning system and method

A system for applying a fiber matrix on a tubular member is provided. A mandrel, configured for atraumatic placement within the tubular member, is included. Methods for atraumatic placement of a mandrel into a tubular member are also provided.

System and mandrel for creating graft devices

A device for orthopedic measurements includes a main housing, a center member, a measurement indicator, and a flexible member. The main housing has a proximal end with a top opening and a distal end with a side opening, and defines a longitudinal axis and includes a main housing cavity. The center member is disposed along the longitudinal axis within the main housing cavity. The measurement indicator is operatively connected to the center member, and is configured and adapted to display a measurement of a distance. The flexible member is threaded through the main housing cavity, and includes a first end and an opposed second end with an eyelet disposed proximate the side opening of the main housing. The eyelet is configured to be drawn away from the main housing, extending the flexible member outward with respect to the side opening to display a measurement on the measurement indicator.

Orthopedic measurement devices, systems and methods

Systems and methods for deploying an implant in the vasculature

Growing community of inventors

Acton, MA, United States of America

Joseph Ting