Alpharx, Inc.

Teva Pharmaceutical Industries Limited

Eastgate Pharmaceuticals Inc.

Joseph Schwarz

Michael Weisspapir

Claude Singer

Julia Hrakovsky

Ruth Tenengauzer

Michael Pesachovich

Lev Khondo

Tania Lessen

Mathi Mathivanan

Peter Louis Carlen

The present disclosure relates to self-emulsifying pharmaceutical compositions for transmucosal delivery of biologically active peptides and proteins.

Composition for intraoral delivery of biologically active peptides and proteins

The present disclosure relates to pharmaceutical compositions of solid dosage form for intraoral administration that provides effective delivery of insulin and insulin analogs via the transmucosal route. Also provided are methods for treating pre-diabetes, diabetes and metabolic syndrome in a subject in need thereof.

Pharmaceutical composition for transmucosal delivery and methods for treating diabetes in a subject in need thereof

There is provided an ophthalmic pharmaceutical preparation comprising menthyl ester of indomethacin as an active ingredient. Also provided are different possible formulations of the ophthalmic preparation, and different methods of treating ophthalmic irritation using the ophthalmic preparation.

Ophthalmic preparation containing menthyl ester of indomethacin

A vehicle for topical delivery which contains a liquid eutectic mixture of hydrophobic compounds.

Vehicle for topical delivery of anti-inflammatory compounds

The stabilization of benzoyl peroxide for extended periods of time is disclosed. The stabilized solution contains from between 0.5% and 20% organic peroxide and a stabilizer for preventing degradation of said peroxide in the solution.

Stabilization of benzoyl peroxide in solution

Compositions and methods of stabilizing azithromycin compositions are described. Stabilized azithromycin compositions comprise an intimate admixture of azithromycin and a stabilizing-effective amount of an antioxidant to improve the resistance of the azithromycin to degradation. Coprecipitation or co-milling of azithromycin and an antioxidant are particularly preferred means of achieving an intimate admixture. Pharmaceutical formulations comprising a stabilized azithromycin composition and methods of making such formulations are also described.

Stabilized azithromycin compositions

Toothpaste incorporating chlorhexidine bigluconate for improved adhesive onto the surface of the teeth. A second embodiment discusses the use of triclosan and in combination with sodium monofluorphosphate for use in the toothpaste.

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Richmond Hill, Canada

Joseph Schwarz