Novartis Ag

Pfizer Corporation

Gilead Sciences, Inc.

Other

Joseph Michael Young

Patrick Robert Verhoest

Thomas Allen Chappie

Nandini Chaturbhai Patel

Simone Sciabola

Jiping Fu

Peichao Lu

Christopher John Helal

Matthew Merrill Hayward

Erik Alphie LaChapelle

Michael Robert Turner

Keith Bruce Pfister

Travis T Wager

Xianming Jin

Wooseok Han

Qian Zhao

Britton Kenneth Corkey

David C Tully

Samuel E Metobo

Jaclyn Louise Henderson

Bethany Lyn Kormos

Naomi S Rajapaksa

Jamison Bryce Tuttle

Subramanian Karur

Patrick Lee

Robert Joseph Moreau

Yipin Lu

Galen Paul Shearn-Nance

Joseph Walter Tucker

Zef Konst

Erik Alphie Lachapelle

Travis T Wagner

The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Antiviral pyrazolopiridinone compounds

The invention relates to compounds of Formula I:

Compounds and compositions for the treatment of cryptosporidiosis

Antiviral pyrazolopyridinone compounds

The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts thereof wherein the variables R, R, R, R, R, a and A are as defined herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D3-mediated (or D3-associated) disorders including, e.g., substance addiction, substance abuse, schizophrenia (e.g., its cognitive symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD or PD), Parkinson's disease, mania, anxiety, impulse control disorders, sexual disorders and depression. 

6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepine dopamine D3 ligands

The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions and pharmaceutical combinations containing such compounds, as well as methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by hepatitis B virus (HBV), and for reducing the occurrence of serious conditions associated with HBV. 

Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals

The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by hepatitis B virus, and reducing the occurrence of serious conditions associated with HBV.

Fused indazole pyridone compounds as antivirals

The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents R, R, R, R, and b are as defined herein. The invention is also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, and methods of preparing the compounds.

Imidazopyridazine compounds

The present invention is directed to pyrazolopyrimine compounds or pharmaceutically acceptable salts which are inhibitors of PDE4 isozymes, especially with a binding affinity for PDE4B isoform, and compositions thereof.

Pyrazolopyrimidine compounds

Tetracyclic pyridone compounds as antivirals

A noise cover system for preventing the noise of a cough, sneeze or the like by a hunter, bird watcher or the like from disturbing birds or animals. The cover is made of flexible thermoplastic neoprene rubber or similar material. The cover is a face mask with a central opening for receiving a face mask. The sides each have a button that can be held to the other side or have a head strap attached. The noise maker has means to make the sound of a crow or other familiar sound, is supported in an opening in the face mask and forcefully exhaled air from a sneeze or cough will actuate the noise maker.

Sound simulating method and device

Growing community of inventors

Castro Valley, CA, United States of America

Joseph Michael Young