Schering Corporation

Joseph Mayer

Margaret H Sherlock

Lydia Peer

Esther Babad

A compound of the formula ##STR1## wherein X and Y are independently selected from hydrogen, halogen, trifluoromethyl, nitro, C.sub.1 to C.sub.6 alkyl and C.sub.1 to C.sub.6 alkoxy, and Z is C.sub.1 to C.sub.6 alkyl or hydrogen is disclosed.

Benzodiazepine intermediates

This invention describes a novel process whereby meta-substituted anilides are nitrated in the para position in high yields.

Process for nitrating anilides

This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.

Process for preparing 1-aminonaphthyridines

1-Aminonaphthyridines

Certain amino naphthyridines

This invention relates to a novel process for preparing 2-halogeno-nicotinic acids. The compounds, especially 2-chloro-nicotinic acid, are intermediates in the preparation of anilino nicotinic acid derivatives. The latter compounds are useful as analgesic anti-diarrheal and anti-inflammatory agents.

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Joseph Mayer