Cardiac Pacemakers, Inc.

Boston Scientific Neuromodulation Corporation

Incon-trol Corp.

Other

Physio-control, Inc.

Boston Scientific Neuromodulation Corporaton

Joseph M Bocek

Jaeho Kim

Harley G White

Dan Li

Jeffrey E Stahmann

Michael A Moffitt

Eric G Lovett

Scott A Meyer

Rosana Esteller

Matthew Lee McDonald

Paul Allan Haefner

Ross Daniel Venook

William Hsu

Michael J Lyden

William J Linder

Yi Zhang

Sridhar Kothandaraman

Julie A Thompson

Scott R Stubbs

Phillip Dewey Foshee, Jr

Michael X Govea

Nicholas J Stessman

John Mathew Adams

Jordi Parramon

Rafael Carbunaru

Clifton A Alferness

David L Perschbacher

Robert J Sweeney

James O Gilkerson

David Peter Finch

Gregory J Sherwood

Douglas R Daum

Emanuel Feldman

Xuan K Wei

Tianhe Zhang

Carlos Alberto Ricci

Alok S Sathaye

Anthony Harrington

Haris Sih

Kiran K Gururaj

Gaurav Gupta

Kenneth R Infinger

Bijan Elahi

Mark Schwartz

Thomas M Bocek

Mizanur Rahman

Benjamin Ettori

Craig S Siegman

Bryan Buchanan

Paul E De Coriolis

Scott Walczak

Karl Stoklosa

Dave Perschbacher

Rebecca Bloomfield Davis

Tony Harrington

Shelley Marie Cazares

Darrell Orvin Wagner

Barry Mitchell Yomtov

Yingbo Li

Yayun Lin

Thomas W Stouffer

Joseph M Smith

Richard Fogoros

Richard S Sanders

Richard Milon Dujmovic, Jr

Robert Graham Lamont

Hiten J Doshi

Lorenzo A DiCarlo

Barry M Yomtov

John Michael Link

Phil Foshee

Douglas T Hakala

James G Osborn

Paul De Coriolis

Chirag M Patel

Paul E deCoriolis

Salomo Murtonen

Haris J Sih

Kenneth Ross Infinger

Harley White

Matthew L Mcdonald

An example of a system for delivering neurostimulation energy to a patient using a plurality of electrodes may include a stimulation circuit and a sensing circuit. The stimulation circuit may be configured to deliver the neurostimulation energy using stimulation electrodes selected from the plurality of electrodes and to control the delivery of the neurostimulation energy. The sensing circuit may be configured to receive one or more neural signals from sensing electrodes selected from the plurality of electrodes and may include a signal processing circuit. The signal processing circuit may include a detection circuit and an analysis circuit. The detection circuit may be configured to detect one or more attributes of neural responses from the received one or more neural signals. The analysis circuit may be configured to analyze the detected one or more attributes of the neural responses for one or more indications of a neurodegenerative disease.

Neurostimulation system with neurodegenerative disease detection

An example of an apparatus for percutaneously delivering neurostimulation energy to a patient and sensing from the patient using a test device placed externally to the patient is provided. The apparatus may include a stimulation lead, a sensing reference electrode, a sensing wire, and a connection system. The stimulation lead may be configured to be percutaneously introduced into the patient to place the one or more electrodes in the patient. The sensing reference electrode may be configured to be placed in the patient. The sensing wire may be connected to the sensing reference electrode and configured to be percutaneously introduced into the patient to place the sensing reference electrode in the patient. The connection system may be configured to mate the lead connector and the wire connector and to provide electrical connections between the lead connector and the test device and between the wire connector and the test device.

Sensing reference electrode for percutaneous neuromodulation trials

An example of a system for delivering neurostimulation energy may include a programming control circuit and a user interface. The programming control circuit may be configured to generate stimulation parameters according to a neurostimulation program including a pattern of interferential stimulation configured to effect asynchronous and/or non-regular activation of nerve fibers by simultaneously delivering a first stimulation current having a first waveform with a first frequency using a first electrode configuration and a second stimulation current having a second waveform with a second frequency using a second electrode configuration. The user interface may be configured to determine the neurostimulation program and to provide the pattern of interferential stimulation with modulation of the first waveform, the second waveform, the first electrode configuration, and/or the second electrode configuration to result in a time-varying beat frequency capable of effecting the asynchronous and/or non-regular activation of the nerve fibers.

Interferential stimulation method and system for neuromodulation

Methods, medical devices, and magnetic resonance imaging (MRI) systems are provided. A patient implanted with a medical device is exposed to a time-varying magnetic field having a signature, thereby inducing mechanical vibrations in at least one component of the medical device. A vibrational characteristic of the mechanical vibrations induced in the component(s) is detected. The vibrational characteristic is analyzed, and the signature of the magnetic field is identified based on the analyzed vibrational characteristic. The medical device is automatically switched from a first operational mode to a second operational mode when the signature is identified.

Systems and method for automatically detecting an MRI environment for patient implanted with medical device

An active implantable medical device (AIMD) for use with a medical lead carrying at least one lead electrode. The AIMD comprises interior electronic circuitry configured for performing a medical function via the medical lead, an electrically conductive case containing the interior electronic circuitry, at least one electrical terminal configured for electrically coupling the electronic circuitry respectively to the lead electrode(s), and an inductive element coupled in series between the electrical terminal(s) and the case. The inductive element is configured for hindering the shunting of electrical current from the at least one electrical terminal to the case that has been induced by electromagnetic interference (EMI) impinging on the medical lead.

Implantable medical device having electromagnetic interference filter device to reduce pocket tissue heating

A neurostimulation device and system are provided. At least one neurostimulation lead having a plurality of electrodes is configured for being implanted within tissue of a patient. A shunt capacitance is coupled to one of the electrodes. Time-varying electrical current is delivered to at least one of the electrodes, wherein the shunt capacitance would, without compensation, absorb charge from or inject charge into the tissue in response to time-varying changes in the delivered electrical current, thereby causing an uncompensated electrical waveform to be delivered to the tissue adjacent the one electrode, The absorbed or injected charge is at least partially compensated for, thereby causing a compensated electrical waveform to be delivered to the tissue adjacent the one electrode.

System and method for electrical pulse charge compensation for implantable medical device capacitance loading effects

Methods and devices for classifying a cardiac pacing response involve using a first electrode combination for pacing and a second electrode combination for sensing a cardiac signal following pacing. The cardiac response to pacing may be classified using the sensed cardiac signal. One process involves using the sensed cardiac signal to detect the cardiac response as a fusion/pseudofusion beat. Another process involves using the sensed cardiac signal to classify the cardiac response to pacing as one of at least three cardiac response types.

Cardiac response classification using multisite sensing and pacing

An implantable medical device capable of being placed between a first operational mode and a second operational mode. The medical device comprises a magnetic field sensing device for outputting a signal in response to sensing a magnetic field. The medical device further comprises a logic circuit for continuously asserting the signal during a time period when the neurostimulation device is in the first operational mode, and intermittently asserting the signal during at least one time period when the neurostimulation device is in the second operational mode. The medical device further comprises a delay circuit for introducing a time delay into the asserted signal, the time delay being less than the time period, but greater than each of the at least one time period. The medical device further comprises control circuitry for performing a function in response to receiving the delayed signal at a first input terminal.

Neurostimulation system for enabling magnetic field sensing with a shut-down hall sensor

A method of estimating response of a medical lead to an electromagnetic field includes providing a medical lead having a proximal end, a distal end, a plurality of electrodes disposed along the distal end, a plurality of terminals disposed along the proximal end, and a plurality of conductors extending along the medical lead and electrically coupling the electrodes to the terminals; individually applying a test field at each of a plurality of test positions along the medical lead using at least one excitation probe; for each application of the test field, determining a response to the application of the test field at one or more of the electrodes or terminals; generating a transfer function using a combination of the responses determined for the applications of the test field; and using the transfer function to estimate a response of the medical lead to an electromagnetic field.

Systems and methods for obtaining and using incident field transfer functions of electrical stimulation systems

An implantable medical device can include a therapy circuit coupled to a therapy delivery terminal, the therapy circuit configured to generate a specified electrostimulation therapy for delivery to a tissue site via the therapy delivery terminal, and a measurement circuit for measuring at least two impedances of a first terminal combination including the therapy delivery terminal, the two impedances corresponding to at least two instances of excitation separated enough in time to capture an impedance artifact due at least in part to a motion of the heart, such as to determine an electrostimulation therapy lead status at least in part using the at least two impedances.

Lead fault detection for implantable medical device

An ambulatory or implantable device, such as a pacer, defibrillator, or other cardiac rhythm management device, can tolerate magnetic resonance imaging (MRI) or other noise without turning on an integrated circuit diode by selectively providing a bias voltage that can overcome an expected induced voltage resulting from the MRI or other noise.

Implantable device with bias for MRI

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Seattle, WA, United States of America

Joseph M Bocek