3m Innovative Properties Company

Minnesota Mining and Manufacturing Company

Riker Laboratories Inc.

Joseph M Beaurline

Jie Jerry Liu

Patrick A Mach

Wensheng Xia

Jason W Bjork

Mark A Tomai

Patrick J Roddy

Robert K Schultz

John T Capecchi

John P Vasilakos

Stephen M Berge

James M Elvecrog

Karen Elizabeth Johnson

Karen E Johnson

James Elvecrog

Injectable formulations comprising ethanol, sesame oil, and an Immune Response Modifier compound are disclosed. Methods of making the formulations and methods of using the formulations for treatment of a disease in a subject, e.g., neoplastic disease, comprising injecting the formulations into a subject hi need of treatment, are also provided.

Sesame oil based injection formulations

A latent effervescent body comprising a selective agent is disclosed. A method of using the latent effervescent body in a method to selectively enrich a target microorganism is also disclosed. The method comprises providing a sample, a culture medium, and the latent effervescent body. The method further comprises contacting the sample, the culture medium, and the latent effervescent body under conditions to facilitate growth of the target microorganism. The method further comprises releasing the selective agent from the latent effervescent body. Optionally, the method includes detecting a microorganism.

Effervescent compositions and uses thereof

Pharmaceutical gel formulations for topical drug delivery include drug, colloidal silicon dioxide, triacetin and, preferably, propylene glycol. The gel formulations are well suited for topical delivery of the drug 4-amino-2-ethoxymethyl-&agr;,&agr;-dimethyl-1H-imidazo&lsqb;4,5-c&rsqb;quinoline-1-ethanol, which when applied topically induces cytokines, such as interferon and tumor necrosis factor, locally in the skin or mucous membranes of a mammal. The gel formulations are also well-suited for topical delivery of drugs for treatment of diseases involving skin and/or mucosal lesions because the gel formulations do not need to include irritating components.

Gel formulations for topical drug delivery

Pharmaceutical gel formulations for topical drug delivery include drug, colloidal silicon dioxide, triacetin and, preferably, propylene glycol. The gel formulations are well suited for topical delivery of the drug 4-amino-2-ethoxymethyl-.alpha.,.alpha.-dimethyl-1H-imidazo�4,5-c!quinoline -1-ethanol, which when applied topically induces cytokines, such as interferon and tumor necrosis factor, locally in the skin or mucous membranes of a mammal. The gel formulations are also well-suited for topical delivery of drugs for treatment of diseases involving skin and/or mucosal lesions because the gel formulations do not need to include irritating components.

A salsalate tablet containing hydroxypropyl cellulose as a binder substantially uniformly dispersed in the tablet. The tablet has good mechanical strength, exhibits a relatively low incidence of capping, and does not require a discrete outer film coating to prevent esophageal irritation.

Salsalate tablet

An aqueous suspension for oral administration of a drug, which suspension is storage stable for a prolonged period and maintains the drug in suspension during such period.

Growing community of inventors

North St. Paul, MN, United States of America

Joseph M Beaurline