Arsenal Medical, Inc.

Olivo Laboratories, LLC

Shiseido Company, Limited

Living Proof, Inc.

Shiseido Americas Corporation

Adaptive Surface Technologies, Inc.

Joseph Lomakin

Soo-Young Kang

Betty Yu

Benjamin W Adams

Gregory T Zugates

John Marini

Jennifer Mortensen

Upma Sharma

Rany Busold

Adam Rago

Jeffrey Groom, Ii

Toby Freyman

Philseok Kim

Stephanie Webber

Janet Komatsu

Teluka Pasan Galhen-Age

In various aspects, present disclosure is directed to methods, devices and systems whereby one or more low viscosity fluids may be introduced into a catheter and whereby the one or more low viscosity fluids may be converted into a high viscosity fluid in the catheter, which high viscosity fluid may be delivered from an exit port of the catheter.

Methods, devices and systems for filling body cavities

Compositions and methods useful in treating dermatological disorders are described. The methods include applying to the skin a composition comprising a reactive reinforcing component and a cross-linking component, wherein the cross-linking component facilitates a reaction to form a film in situ on the skin.

Compositions and methods for treating conditions of compromised skin barrier function

The present invention provides durable, natural looking, non-invasive compositions that exhibit desired aesthetic qualities for therapeutic treatments. Specifically, the compositions can be used for the treatment of wounds and headaches. In addition, the compositions of the invention can be used to deliver agents to the subject in need thereof. In one embodiment, the invention pertains, at least in part, to methods for treating wounds, comprising applying to a subject's skin a formulation comprising a) a first reactive reinforcing component; and b) a second cross-linking component; in which the cross-linking component catalyzes an in situ cross-linking of the reactive reinforcing component, such that a film is formed on the wound, thereby treating the wound.

Skin compositions and methods of use thereof

Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.

Systems and methods for the treatment of aneurysms

Compositions and methods useful for delivering an agent to a subject are described. The methods include applying to the subject's skin a composition comprising a reactive reinforcing component, a cross-linking component, and one or more agents, wherein the cross-linking component catalyzes an in situ reaction on the skin, thereby delivering the agent to the subject.

Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.

In-situ forming foams with outer layer

Provided are body corrective cosmetic formulations and methods of use thereof.

This invention relates to compositions and methods useful in treating dermatological disorders. In particular, the methods include applying a composition that includes a reactive reinforcing component; and a cross-linking component; in which the cross-linking component facilitates in situ cross-linking of the reactive reinforcing component, such that a film is formed on skin, thereby treating the dermatological disorder.

The present invention provides durable, natural looking, non-invasive compositions that exhibit desired aesthetic qualities. Specifically, the compositions can be used for therapeutic treatments, including treatments of wounds and headaches. The invention pertains, at least in part, to therapeutic formulations for application to the skin that comprise a) a reactive reinforcing component; and b) a cross-linking component; in which the cross-linking component facilitates in situ formation of a film over the skin.

Growing community of inventors

Cambridge, MA, United States of America

Joseph Lomakin