Allred & Associates, Inc.

Propulsive Wing, LLC

Syracuse University

Edge Pharma, LLC

Joseph Kummer

Jimmie B Allred, Iii

Michael D Griswold

Michael J Hall

Matthew A Bush

Thong Dang

Edmund Zielinski

Brian Thomas Badgley

Sara Jane Nadeau

Steven David Kummer

William Marc Chatoff

Melissa Lee Bainbridge

The disclosure provides compositions, methods, and devices for use in delivering Mitomycin-C(MMC), an antineoplastic chemotherapy drug often used for bladder instillations to treat bladder cancer, which degrades in both acidic and alkaline environments. The disclosure provides a solution of buffered MMC (or a different drug) in 50% propylene glycol that maintains a pH from 7.0 to 8.0 when introduced into acidic solutions (pH of 5.0) and is stable when stored at 2-8&#xb0; C. for greater than 134 days. This formulation can be produced in an FDA registered 503B Outsourcing facility in a pre-filled, ready-to-administer syringe kit with pre-attached closed system transfer device and accessories required for bladder instillation.

Mitomycin-C bladder instillation syringe kit

A hybrid axial/cross-flow fan aerial vehicle includes both axial and cross-flow fan propulsion for efficient hover and forward flight performance. The axial fans provide primarily vertical thrust, while the cross-flow fan provides horizontal, as well as vertical, thrust. The vehicle takes off vertically, is capable of hover, and can fly forward by vectoring the thrust of the cross-flow fan system. This approach provides large internal cargo capacity and high forward flight speeds.

Hybrid axial/cross-flow fan multi-rotor aerial vehicle

A dual-use ladder and bridge modular system preferably includes tubes, gussets, flanges, and/or joints. In a preferred embodiment, the tubes, gussets, flanges, and/or joints are made of carbon fiber. A method connects and disconnects modular carbon fiber ladder segments. Another method creates a lightweight carbon-fiber beam with exceptionally high stiffness and strength using a combination of carbon-fiber braid material, uni-directional cloth, and pultruded carbon-fiber strips. A carbon fiber ladder segment and tube connectors are also disclosed.

Dual-use modular carbon-fiber ladder and bridge

A c-shaped clamp tool system preferably includes slider arms, one or more slider arm supports, pads, one or more threaded rods, and turning knobs. The clamping system preferably includes multiple slider arms and slider arm supports of different lengths. In a preferred embodiment, the slider arms are made of unidirectional pultruded carbon fiber and the slider arm support is made of woven carbon fiber.

Adjustable c-clamp system

Ultra lightweight segmented ladder/bridge system

The present invention includes a system for connecting tubes or rods, which are preferably uni-directional pultruded, filament wound, or roll-wrapped carbon-fiber tubes or rods, together to form trusses and other structures using a series of connector pieces preferably bonded together with adhesive.

3-dimensional universal tube connector system

A ventilation device uses a cross-flow fan and one or more filters, where the filter preferably has a J-shape that at least partially surrounds the rotor of the cross-flow fan. In one embodiment, the filter includes a plurality of pleats, preferably along a bottom surface of the filter. The filters preferably remove particles, undesired gases, and micro-organisms. A filtration and ventilation system with at least one first ventilation device and at least one second ventilation device larger than the first ventilation device, as well as a method of filtering contaminants out of air using a personal ventilation device, are also disclosed.

Multi-use personal ventilation/filtration system

A personal ventilation system uses a cross-flow fan and one or more filters, where the filter preferably has a cylindrical or elongated elliptical shape that at least partially surrounds the rotor of the cross-flow fan. The filters preferably remove particles, undesired gases, and micro-organisms.

A cross-flow propulsion mechanism for use in providing propulsion to an aircraft, includes a housing defining an inlet, a rotor compartment, and an outlet. The inlet is adapted to receive an inflow of air along a first longitudinal axis. The rotor is mounted within the rotor compartment and adapted to receive the airflow introduced into the housing through the inlet and rotate about a second longitudinal axis that is substantially perpendicular to the first longitudinal axis. The outlet is adapted to receive the airflow processed through the rotor and exhaust air along a third longitudinal axis that is substantially parallel to the first longitudinal axis. The propulsion mechanism can be applied in a personal aircraft, an STOL aircraft, and a hybrid automobile and aircraft.

Growing community of inventors

Fayetteville, NY, United States of America

Joseph Kummer