The Salk Institute for Biological Studies

Other

Joseph Jez

Joseph Noel

Marianne Bowman

Rebecca E Cahoon

Philip A Rea

Jean-Luc Ferrer

Mike Austin

Transgenic plants exhibiting phytochelatin-based heavy metal tolerance and methods of use thereof for bioremediation are disclosed.

Transgenic plants exhibiting enhanced phytochelatin-based heavy metal tolerance and methods of use thereof

This disclosure provides crystalline flavonoid or flavanone isomerases, isolated non-native isomerase having the structural coordinates of said crystalline isomerase, and nucleic acids encoding such non-native isomerase. Also disclosed are methods of predicting the activity and/or substrate specificity of a putative isomerase, methods of identifying potential ismerase substrates, and methods of identifying potential isomerase inhibitors.

Chalcone isomerase polypeptides and crystals thereof

This disclosure provides crystalline flavonoid or flavanone isomerases, isolated non-native isomerase having the structural coordinates of said crystalline isomerase, and nucleic acids encoding such non-native isomerase. Also disclosed are methods of predicting the activity and/or substrate specificity of a putative isomerase, methods of identifying potential isomerase substrates, and methods of identifying potential isomerase inhibitors.

Three-dimensional structure of chalcone isomerase and methods of use thereof

The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic acids encoding such non-native polyketide synthases. Also disclosed are methods of predicting the activity and/or substrate specificity of putative polyketide synthase, methods of identifying potential polyketide synthase substrates, and methods of identifying potential polyketide synthase inhibitors.

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Kirkwood, MO, United States of America

Joseph Jez