Depuy Mitek, Inc.

Ethicon, Gmbh

Agency for Science, Technology and Research

Ethicon Endo-surgery, Inc.

Advanced Technologies and Regenerative Medicine, LLC

Joseph J Hammer

Joel S Rosenblatt

Francois Binette

Krish Mukhopadhyay

Murty Narayan Vyakarnam

Prasanna Malaviya

Kevin L Cooper

Joseph Henry Contiliano

Sridevi N Dhanaraj

Julia Hwang

Hong Yee Low

Sriram Natarajan

Stephanie M Kladakis

Dhanuraj Shetty

Kelly R Brown

Isabel Rodriguez

Chee Tiong Lim

Audrey Yoke Yee Ho

Herb Schwartz

Alireza Rezania

Herbert Eugene Schwartz

Mark D Timmer

Iksoo Chun

Mora Carolynne Melican

Victor F Janas

Mark C Zimmerman

Jennifer Mandanas

François Binette

An implant having an adhesive structure comprising a planar surface having two sides and rectangular cuboid-based protrusions having pyramidal tips extending from at least one of said sides, optionally having a porous basic supporting structure, and methods of making and using such implants.

Adhesive structure with tissue piercing protrusions on its surface

A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.

Adhesive structure with stiff protrusions on adhesive surface

A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.

Scaffold for connective tissue repair

A conformable tissue implant is provided for use in repairing or augmenting a tissue defect or injury site. The tissue implant contains a tissue carrier matrix comprising a plurality of biocompatible, bioresorbable granules and at least one tissue fragment in association with the granules. The tissue fragment contains one or more viable cells that can migrate from the tissue and populate the tissue carrier matrix. Also provided is a method for injectably delivering the tissue implant.

Conformable tissue repair implant capable of injection delivery

A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.

Nonwoven tissue scaffold

The present invention relates to tissue scaffold implant devices useful in the repair and/or regeneration of diseased and/or damaged musculoskeletal tissue and that include a tissue scaffold component fixedly attached to a scaffold fixation component via a polymeric adhesive layer, and to methods of making such tissue scaffold implant devices.

Attachment of absorbable tissue scaffolds to fixation devices

An implantable biodegradable device is disclosed containing a fibrous matrix, the fibrous matrix being constructed from fibers A and fibers B, wherein fibers A biodegrade faster than fibers B, fibers A and fibers B are present in relative amounts and are organized such that the fibrous matrix is provided with properties useful in repair and/or regeneration of mammalian tissue.

Implantable biodegradable devices for musculoskeletal repair or regeneration

The present invention relates to tissue scaffold implant devices useful in the repair and/or regeneration of diseased and/or damaged musculoskeletal tissue and that include a tissue scaffold component fixedly attached to a scaffold fixation component via at least one of sutures, fabrics, fibers, threads, elastomeric bands, reinforcing elements and interlocking protrusions for engaging and maintaining the scaffold component fixedly attached to the fixation component.

Growing community of inventors

Hillsborough, NJ, United States of America

Joseph J Hammer