Hampshire Chemical Corp.

Sciessent LLC

Difusion Technologies, Inc.

W. R. Grace Co.-conn.

Chuckles, Inc.

Difusion, Inc.

Joseph J Crudden

Derrick Johns

Joseph V Lazzaro

Brian A Parker

Jami Hafiz

John R Pepper

Arthur M Nonomura

James Edward Deaton

Barry A Cullen

Peter Whang

John J Nishio

Edward K Welch, Ii

Charles P Frank

Sriram Sankar

James E Steffel

Gary Ghiselli

John M Crudden

Derrick W Johns

Anti-biofilm osseointegrating and/or tissue-integrating implantable biomaterial devices that optionally can elute therapeutic ions such as magnesium, silver, copper and/or zinc. In certain embodiments, the devices are engineered to produce structures suitable as implants having a relatively high surface population of zeolite. Methods of producing the devices are also disclosed.

Medical implants and methods of manufacture

Methods of post-loading ceramic particles with antimicrobial metal cations are disclosed. In certain embodiments, the post-loaded particles are zeolites, wherein the zeolites have been incorporated into a resin and the combination is used as an implantable device. In certain embodiments, the polymer is a thermoplastic polymer such as polyaryletheretherketone (PEEK). In certain embodiments, the source of antimicrobial activity includes ion-exchangeable cations contained in a zeolite. In certain embodiments, disclosed are methods of imparting antimicrobial activity to devices by controlling the delivery of certain cations through ion-exchange via a zeolite incorporated in the device.

Post-charging of zeolite doped plastics with antimicrobial metal ions

Devices such as orthopedic implants are composed of a thermoplastic resin such as polyaryletheretherketone (PEEK), and include a ceramic species, such as a zeolite, to enhance its hydrophilic properties. The ceramic species can be a surface coating, can be incorporated or embedded into the thermoplastic resin, or can be both a surface coating and incorporated or embedded into the resin. In certain embodiments, the ceramic species is zeolite that is incorporated into the device, especially at the exposed surface of the device, and is devoid of antimicrobial metal ions. The device is introduced into the body surgically.

Medical implants with increased hydrophilicity

Seeds having applied to their surface a bioactive agrichemical composition comprising metal-acid solutions for protecting the seed from the adverse action of microorganisms.

Bioactive acid agrichemical compositions and use thereof

Methods of fabricating implantable medical devices, preferably with PEEK, having antimicrobial properties, are disclosed. The antimicrobial effect is produced by incorporating ceramic particles containing antimicrobial metal cations into molten PEEK resin, which is subsequently allowed to cool and set in its final shape achieved by injection molding, cutting and machining or other techniques.

Method of manufacturing antimicrobial implants of polyetheretherketone

Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.

Keratinous fiber treatment formulations and methods of providing a long lasting set in keratinous fibers such as hair by applying a polymer system to the hair which provides a stable set to the hair which will last at least until the hair is thoroughly washed. The set is made more permanent by incorporating a reducing agent such as L-cysteine into the polymer system and allowing the system to air oxidize over time or optionally applying a second chemical oxidizing system to the treated hair which will accelerate the oxidation process and the setting rate of the hair.

Rapid permanent hair setting formulation, system and method

A method of protecting food or delaying the onset of food spoilage said method comprising applying a protective bioactive composition to the food or the packing or packaging in which the food is stored.

Food preservation compositions and methods

Bioactive agrichemical compositions and use thereof

Bioactive agrichemical concentrates and compositions having improved bioactivity comprising metal-acid solutions.

Efficient antimicrobial additives are provided comprising a wettable, cake-forming inorganic material having dispersed therein an inorganic or organometallic antimicrobial agent capable of releasing antimicrobial metal ions. These antimicrobial additives are especially effective for use in cements, mortars and cementitious compositions.

Growing community of inventors

Hudson, NH, United States of America

Joseph J Crudden