Massachusetts Institute of Technology

Other

Joseph J Baraga

Richard P Rava

Michael S Feld

Rebecca Rae Richards-Kortum

Carter Kittrell

Ramachandra Rac Dasari

Robert M Cothren

Kyungwon An

Lucene Tong

Paola Taroni

Young D Park

Anand V Mehta

Systems and methods for spectroscopic diagnosis and treatment are employed which utilize molecular spectroscopy to accurately diagnose the condition of tissue. Infrared Raman spectrscopy and infrared attenuated total reflectance measurements are performed utilizing a laser radiation source and a fourier transform spectrometer. Information acquired and analyzed in accordance with the invention provides accurate details of biochemical composition and pathologic condition.

Systems and methods of molecular spectroscopy to provide for the diagnosis of tissue

Systems and methods for spectroscopic diagnosis and treatment are employed which utilize molecular spectroscopy to accurately diagnose the condition of tissue. Infrared Raman spectroscopy and infrared attenuated total reflectance measurements are performed utilizing a laser radiation source and a fourier transform spectrometer. Information acquired and analyzed in accordance with the invention provides accurate details of biochemical composition and pathologic condition.

Methods of molecular spectroscopy to provide for the diagnosis of tissue

A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.

Method for laser induced fluorescence of tissue

The present invention relates to a method of generating and processing spectral information arising from the laser induced fluorescence of tissue. The intensity of fluorescence is recorded as a function of both excitation and emission wavelengths and contour maps of tissue fluorescence are generated which are useful in the diagnosis of condition of the tissue under examination.

Contour mapping of spectral diagnostics

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Somerville, MA, United States of America

Joseph J Baraga