University of Massachusetts

Analiza, Inc.

Medical University of Graz

Joseph Horowitz

Yossi Chait

Christopher V Hollot

Daniel Schneditz

Michael J Germain

Hamed Samandari

Michael Jack Germain

William Charles Vogt

Absolute blood volume in dialysis patients is a useful patient attribute to know for dialysis treatment, diagnosis, adjustments, etc. In some cases, it is difficult or impossible to directly determine absolute blood volume. Estimating absolute blood volume may be used to overcome the inability to directly determine the absolute blood volume. Estimating absolute blood volume may include obtaining a series of measurements of hemoconcentration of a patient over a time period, and estimating parameters for a physiological model based on the series of measurements. The absolute blood volume of the patient may be determined using the physiological model.

Absolute blood volume estimation device and method

The present invention is generally directed to methods and devices for determining dosing for a medical agent. In some embodiments, a mathematical algorithm is employed for computing erythropoiesis-stimulating agents dosing for treating anemia in a subject, e.g., a human subject. Any suitable dosing may be used, e.g., intravenous, subcutaneous, or oral dosing. In some cases, dosing for a wide range of subject types and health conditions can be achieved using the devices and methods disclosed herein.

Methods and devices for determining optimal agent dosages

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Amherst, MA, United States of America

Joseph Horowitz