New York University

Advanced Veterinary Technologies, Inc.

Medical University of South Carolina

Musc Foundation for Research Development

New York State Department of Mental Hygiene Office of Mental Health

Joseph Helpern

Jens Jensen

Els Fieremans

Ali Tabesh

Ramesh Chandra

Craig Branch

Glyn Johnson

Dmitry Novikov

Alexey S Peshkovsky

Sai Kam Hui

Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and determining a measure of a diffusional kurtosis as a function of the received data using a closed form solution procedure. In accordance with certain exemplary embodiments of the present disclosure, provided herein are computer-accessible medium, systems and methods for, e.g., imaging in an MRI system, and, more particularly for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging (DKI). For example, DKI can facilitate a characterization of non-Gaussian diffusion of water molecules in biological tissues. The diffusion and kurtosis tensors parameterizing the DKI model can typically be estimated via unconstrained least squares (LS) methods. In the presence of noise, motion, and imaging artifacts, these methods can be prone to producing physically and/or biologically implausible tensor estimates. The exemplary embodiments of the present disclosure can address at least this deficiency by formulating an exemplary estimation problem, e.g., as linearly constrained linear LS, where the constraints can ensure acceptable tensor estimates.

System, method and computer accessible medium for providing real-time diffusional kurtosis imaging and for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging

One aspect of the present disclosure relates to a system that can perform double pulsed diffusional kurtosis imaging (DP-DKI). Image data can be received. The image data can be acquired using a double pulsed field gradient (d-PFG) diffusion sequence. A six dimensional (6D) diffusional kurtosis for the image data can be determined. A magnitude of the image data can be determined in terms of the 6D diffusional kurtosis. DP-DKI can isolate the contributions to the d-PFG diffusion sequence, which can represent leading diffusion effects, that cannot be seen from single pulsed field gradient (s-PFG) diffusion sequences.

Systems and methods for double pulsed diffusional kurtosis imaging

One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.

Systems and methods for determining white matter fiber tractography

Exemplary embodiments of a methodology, procedure, system, method and computer-accessible medium can be provided to obtain particular information relating to at least one transport property of a material containing at least one membrane, and to determine, e.g., a permeability of the membrane of the material and/or a surface area of the membrane of the material, as a function of, e.g., the obtained particular information.

System, method and computer-accessible medium for determining membrane properties relating to diffusion

Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function ('MFC'), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences ('ADSE') and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (&#x201c;EPI-ADSE&#x201d;) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

Method, system and software arrangement for measuring magnetic field correlation

Method, system and software arrangement, for measuring magnetic field correlation

An apparatus and method for providing RF shielding for performing nuclear magnetic resonance ('NMR') procedures, comprising a radio-opaque holder in combination with radio-opaque magnet components to form an RF shield around a patient undergoing an NMR procedure. In embodiments, a radio-opaque holder having a radio-opaque bottom portion and a radio-opaque canopy is adjoined to an NMR magnet having a radio-opaque cryostat and a radio-opaque service end cap to form an RF shield. A patient is placed on a patient support unit located in the holder bottom portion. The patient support unit, including the patient, is then inserted into the cavity of the NMR magnet and a canopy is placed on top of the bottom portion of the holder. An RF shield is thus created comprising the canopy, the bottom portion, the cryostat of the magnet, and an end cap on the service end of the magnet.

Method for providing RF shielding for a nuclear magnetic resonance apparatus

Radio frequency shield for nuclear magnetic resonance procedures

A magnetic resonance imaging ('MRI') system and method of correcting for the motion of a subject during an MRI scan. The motion of a subject in an MRI scan is corrected by acquiring nuclear magnetic resonance ('NMR') spectra of an ordered material attached to a subject, wherein there is a dependence on the NMR spectra of the ordered material's orientation in a magnetic field, and determining an orientation of the subject. Correction information is then supplied to a primary spectrometer channel which is used to execute an MRI scan, and an imaging pulse sequence of the MRI scan is adjusted to correct the subject's orientation.

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Cornwall, NY, United States of America

Joseph Helpern