Allergan, Inc.

Advanced Medical Optics, Inc.

Other

Abbott Medical Optics Inc.

Joseph G Vehige

Peter A Simmons

Richard S Graham

Joan-En Chang-Lin

James Nienyuan Chang

Chin-Ming Chang

Robert T Lyons

Teresa H Kuan

Wendy M Blanda

David A Marsh

Steven S Matsumoto

James P Currie

Bereth J Beard

Liu Haixia

Richard Graham

Provided herein are low salt ophthalmic pharmaceutical composition and methods of use thereof, for example, in the treatment of dry eye syndrome.

Efficient lipid delivery to human tear film using a salt-sensitive emulsion system

Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and/or the adverse effects of cationic species on the ocular surfaces of eyes and/or to facilitate recovery from eye surgery.

Ophthalmic compositions and methods for treating eyes

The present invention relates to ophthalmic compositions and methods useful to treat dry eye, or to diagnose, cure, mitigate, treat, or prevent dry eye syndrome in man or other animals.

Compositions for the treatment of dry eye

The present invention provides for compositions for administering a therapeutically effective amount of a therapeutic component. The compositions may include an ophthalmically acceptable carrier component; a therapeutically effective amount of a therapeutic component; and a retention component which may be effective to reduce wettability, induce viscosity, increase muco-adhesion, increase meniscus height on a cornea of an eye and/or increase physical apposition to a cornea of an eye of a composition.

Compositions for delivery of therapeutics into the eyes and methods for making and using same

Solutions useful to clean contact lenses include a surfactant component in an effective amount; and a viscosity inducing component, preferably selected from cellulosic derivatives and more preferably hydroxypropylmethyl cellulose, in an effective amount. Such solutions, which may include one or more additional components, have substantial contact lens cleaning benefits which, ultimately, lead to ocular health advantages and avoidance of problems caused by contact lens wear.

Contact lens cleaning compositions

Multi-purpose solutions for contact lens care provide substantial lens wearer/user comfort and/or acceptability. Such solutions include an aqueous liquid medium; an antimicrobial component, preferably a biguanide polymer present in an amount of less than about 5 ppm; a surfactant component, preferably a poly(oxyethylene)-poly(oxypropylene) block copolymer surfactant, in an effective amount; a phosphate buffer component in an effective amount; a viscosity inducing component, preferably selected from cellulosic derivatives, in an effective amount; and a tonicity component in an effective amount. Such solutions have substantial performance, comfort and-acceptability benefits, which, ultimately, lead to ocular health advantages and avoidance of problems caused by contact lens wear.

Multi-purpose contact lens care compositions

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Laguna Niguel, CA, United States of America

Joseph G Vehige