Scientific Industries, Inc.

Other

Sigma Instruments, Inc.

Joseph G Cremonese

Douglas J Koebler

Michael Tolosa

Brookman P March

William Chandler

John B Crunick

Tamas Becse

Lou L Laskey, Jr

Embodiments of a cell culture monitoring system are disclosed that may include a device having collimating and filtering components to elicit and detect fluorescence from a substrate located within a reaction vessel. The device may be used to detect changes in pH and dissolved oxygen levels in a liquid contained in the reaction vessel due to growth of living cells. Excitation light beams can be generated and collimated by a beam combiner and directed into the reaction vessel so as to be incident upon the substrate to cause the substrate to fluoresce. Some embodiments include use of expected wavelength offsets and shifted filters/mirrors to improve functionality and reduce space of device components.

Apparatus for detecting pH and dissolved oxygen

Biocompatible bag with integral sensors

A device and process for measurement and treatment of spinal mobility is disclosed. The device includes an impulse and sensing head capable of determining spinal segment mobility by applying a force impulse to a spinal segment and generating a waveform characteristic of spinal mobility. An inclinometer disposed within the head determines the angle of incidence of the head in contact with the spinal segment in at least one, preferably three, axis. Characteristics of the waveform and the angle of incidence are analyzed to determine spinal mobility. The information in the waveform and device are then used to treat the patient by applying an oscillating head to a spinal segment so that spinal mobility is increased.

Device and process for measurement and treatment of spinal mobility

A cell culture flask includes a hollow housing and a gas permeable membrane disposed within the housing which divides the housing into a first chamber and a second chamber. A retaining ring secures the gas permeable membrane within the housing and forms a liquid-tight seal between the first chamber and the second chamber. A gas inlet in the housing communicates with the first chamber and supplies gas thereto. A media inlet in the housing communicates with the second chamber and provides cell growth media thereto.

Cell culture flask utilizing a membrane barrier

Growing community of inventors

Greensburg, PA, United States of America

Joseph G Cremonese