Ethicon, Gmbh

Ethicon Endo-surgery, Inc.

Johnson & Johnson Consumer Inc.

Joseph F Zavatsky

Chetan Anirudh Khatri

Bret William Smith

Thomas W Lytle, Iv

Binoy K Bordoloi

Kreena Rajeev Modi

Matthew C Miller

Aron O Zingman

Yi-Lan Wang

Aruna Nathan

Susan Daly

Christopher G Levins

Benjamin D Fitz

Charles J Scheib

Chad Paul Boudreaux

Mark D Overmyer

Michael E Setser

Edward A Rhad

Stephen J Balek

Matthew D Holcomb

Thu Anh Le

Brian W Bear

Donald F Wilson, Jr

Olajompo Moloye-Olabisi

Christopher M Westergom

Rebecca Leibowitz

Elizabeth Vailhe

Sandra Gensini

Nathan Aruna

A polymer composition comprising a linear ultraviolet radiation absorbing polyether that comprises a chemically bound UV-chromophore.

Ultraviolet radiation absorbing polyethers

A modular end effector delivers a therapeutic agent onto tissue that has been severed and/or stapled. The end effector is removably attached to a device. The device applies force to a piston of the end effector. The force causes a distal movement of a piston along a wall disposed within the end effector. The piston engages with agents stored on opposite sides of the wall, moving the agents distally to a mixture space. The agents are mixed in the mixture space and expelled through a tip. Staples may be embedded in or disposed below a foam block, which is disposed within a staple cartridge. Via an endoscopic stapling device, coated staples are driven through tissue while interacting with another agent on the device or the cartridge. The interaction forms a tissue restoring material that is applied onto the tissue.

Device for applying adjunct in endoscopic procedure

A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a removable cartridge when in an open position. The cartridge includes a housing, a plurality of staples disposed in the housing, and a deck disposed over the plurality of staples. The deck defines apertures, with each aperture being substantially disposed over each staple. The instrument includes a movable buttress that is integral with the housing of the cartridge or integral with the lower jaw of the end effector. The buttress may attach to the anvil and include a portion to receive tissue. The receipt of tissue urges and moves the buttress proximally inwards to further encompass the tissue.

Surgical staple cartridge with self-dispensing staple buttress

A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a removable cartridge. The cartridge includes a housing, a plurality of staples disposed in the housing, and a deck disposed over the plurality of staples. The deck defines apertures, with each aperture being substantially disposed over each staple. The cartridge further includes an agent. The firing bar is operable to assist with releasing the agent onto a severed line of tissue when the firing bar is advanced.

Surgical stapling device with adjunct material application feature

A device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device. In particular, the device is an integrated dressing for catheters comprising a pad and an adhesive dressing.

Integrated dressing device

A novel macromer or mixture thereof is described herein, comprising isocyanatophenyl ether terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the ether group of the isocyanatophenyl ether terminal isocyanate moieties, thereby forming at least two ether linkages in the macromer or mixture thereof. A method for making a polyisocyanate macromer is also described herein.

Isocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant

The present invention is directed in one embodiment to a tissue adhesive or sealant composition comprising an electrophilic group containing cross-linking compound having a linker moiety of a diglycolic acid, a water soluble core moiety and an electrophilic group that is covalently bonded to the diglycolic acid linker moiety and a nucleophilic group containing protein. In other embodiments, the present invention is directed to a delivery device or a medical device on which the composition has been applied or incorporated therein. The present invention is also directed to a method for sealing tissue using the tissue adhesive or sealant composition.

Tissue sealants from plasma derived proteins

The invention relates to a novel moisture activated solvent-free latent curing adhesive or sealant mixture comprising (1) a selected poly(alkylene oxide)imine, and (2) a selected amine reactive moiety.

Solvent-free moisture activated latent curing surgical adhesive or sealant

The invention relates to a novel poly(ethylene oxide)imine; a novel amine reactive moiety; a novel moisture activated latent curing adhesive or sealant mixture comprising (1) a ketimine or aldimine, and (2) an amine reactive moiety; and a novel moisture activated latent curing adhesive or sealant comprising the reaction product of (1) and (2).

Moisture activated latent curing adhesive or sealant

The present invention is directed to a medically acceptable formulation comprising a diisocyanate terminated macromer or mixture thereof, and bio-absorbable desiccant comprising a hygroscopic and/or hydrophilic or combination thereof. The present invention is also directed to methods of use for such formulations for medical procedures.

Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant

Growing community of inventors

Flemington, NJ, United States of America

Joseph F Zavatsky