Cook Biotech, Inc.

Cook Medical Technologies LLC

Oregon Health & Science University

Cook Incorporated

Cook Urological, Inc.

Joseph F Obermiller

Dusan Pavcnik

Thomas A Osborne

Andrew K Hoffa

Brian L Bates

Christopher G Dixon

Josef Rosch

John A DeFord

Frederick S Keller

Raymond B Leonard, Ii

Brian C Case

Patrick C Melder

Joseph W Roberts

Ryan Bernstein

P Arun Mohan

Christine Bronikowski

Ram H Paul, Jr

Jacob A Flagle

Michael C Hiles

Fred T Parker, Jr

Clay D Fette

Rodney W Bosley, Jr

Michael L Garrison

John A Kaufman

Steve Chen

Fred T Parker

Jason A Mead

Patricia E Thorpe

Martina Bastin Pavcnik

Francisco Jose Osse

John Kaufman

Francisco Jose Osee

Rodney W Bosley

Tissue adjustment implants useful for adjusting a position of tissue in a patient are described. In an embodiment, a tissue adjustment implant includes a main body having a series of outwardly-extending projections. The tissue adjustment implants can be used in a variety of treatments, such as in the treatment of Obstructive Sleep Apnea and snoring.

Tissue adjustment implant

An apparatus which includes a closure member and delivery systems for closing vessels in the body of a patient is disclosed. In one embodiment, the closure member is a hemostatic closure member having a cylindrical shape and an expandable volume on contact with fluids. The hemostatic member includes a functional passageway through the length of the member so that it may be mounted over a delivery catheter or wire guide for delivery against a vessel puncture or into another vacuslar environment, such as to fill an aneurysm sac. In another embodiment the closure member is a fallopian tube closure member which is deployed into the fallopian tube over a guide wire to prevent conception. The fallopian tube member includes a loop-shaped frame having barbs, a first layer of material, a binding wire, a second layer of material, and an expandable volume on contact with fluids.

Vessel closure member, delivery apparatus, and method of inserting the member

The invention includes a medical device and more specifically relates to a valve found generally within a frame. In a preferred device, the frame preferably comprises a self-expanding stent frame, and the valve has at least one expandable and contractible pocket member within the stent frame for resisting and permitting fluid flow, respectively.

Stent valves and uses of same

Described are hemostasis devices useful for implantation in biopsy tracts, which device comprise highly compact, dried hemostatic sponge elements. Preferred devices also include compacted sponge matrices exhibiting high density and rigidity in combination with high volumetric expandability when wetted. Also described are methods for making and using such devices.

Porous sponge matrix medical devices and methods

A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.

Implantable vascular device

A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.

A stent tissue graft prosthesis () for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent () of which a tissue graft () and preferably a multilayered tissue construct () is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material () such as small intestine submucosa () for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member () such as an outer expandable stent () for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.

Stent tissue graft prosthesis

Implantable medical devices comprising a support frame and a graft member attached to the support frame. The support frame can define one or more structural features that substantially prevent migration of the graft member along the support frame.

Intraluminal support device with graft

Medical devices with one or more bioactive agents are provided for regulating fluid flow through a body vessel. Medical devices according to the invention can comprise prosthetic valves that include a bioactive agent.

Medical device with bioactive agent

The present invention provides self-expanding or otherwise expandable artificial valve prostheses for deployment within a bodily passageway, such as a vessel or duct of a patient. The valve prostheses include a support structure having an outer frame and supporting a valve leaflet.

Artificial valve with center leaflet attachment

Growing community of inventors

Bloomington, IN, United States of America

Joseph F Obermiller