Cardinal Health 414, LLC

Battelle Memorial Institute

Cytyc Corporation

Joseph Edward Zambanini

Thomas Alan Klausing

David Arthur Holley

Brian Charles Kelley

Mehmet Husnu

Jeffrey Taylor Stroup

Dennis Eshima

Gregory A Trees

Chad Edward Bouton

Herman P Benecke

Daniel B Garbark

James A Prescott

Scott Nicholas Danhof

R Reade Harpham

Eric Hassenpflug

James J Lind

James B Gleeson

Derrick Alcaide

Brian Graham

James Stone

Henry Padgett

David J Zahniser

Garrick L Maenle

Matthew S Zelinski

William J Knox

Ted S Geiselman

Howard L Greene

Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceutical output; and providing software and hardware controls for overall and sub-portion operation for optional remote data collection, communication, and/or control.

Systems, methods and devices for producing, manufacturing and control of radiopharmaceuticals

Compact modular cassette systems and methods for the synthesis of radiopharmaceutical products are provided, the compact modular cassette system including a modular unit having valve plates, a reaction cassette, a reagent pack, and other seal and connector plates to ensure that reagents can be mixed together inside one or more chambers of the reaction cassette in a timely and efficient manner. When a new chamber for each new reaction or process should be used, a valveless modular system having removable reaction cassettes and the reagent packs may be used. In such a system, the reagent container, the reaction cassette, or both, can be removed from the modular cassette system and discarded after a desired reaction or process has taken place.

Modular cassette synthesis unit

A cartridge for a handheld electrohydrodynamic (EHD) spraying device and a spraying device incorporating the cartridge. The cartridge is disposable, and can contain therapeutic products. The device includes a wetted lead screw with a compliant seal, where the placement of the seal relative to the screw inhibits leakage during both cartridge use and storage. A frame disposed within the cartridge acts as a load-transferring mechanism for the weight of the cartridge to a handle of the spraying device.

Handheld sprayer with removable cartridge and method of using same

Methods, systems, and computer software for screening and assisting in screening biological specimens. Images of a biological specimen are obtained, and image data is generated from the images. Objects of interest (OOI) are identified from the image data. The OOIs are assigned to each of a plurality of fields of interest (FOIs), at least partially based on the assignment of OOIs to other FOIs. For example, OOIs that have not previously been assigned to other FOIs can be assigned to a selected FOI. In this manner, the OOIs can be grouped within the FOIs to maximize the number of OOIs included within FOIs, or alternatively, to minimize the number of FOIs required to include all of the OOIs. Once assignment of the OOIs is complete, a field of view (FOV) can be scanned relative to each FOI in order to present the OOIs to a technician, such as a cytotechnologist.

Method and system for organizing multiple objects of interest in field of interest

Growing community of inventors

Delaware, OH, United States of America

Joseph Edward Zambanini