Siemens Healthcare Diagnostics Gmbh

Dade Behring Inc.

Dade International Inc.

Joseph Edward Kegelman

Mark Richard Lloyd

John Paul Mizzer

Allan Tit-Shing Chow

Paul John Zuk

Jeffrey Kenneth Parmer

Robert Kyle Wiedenmann

Edward Anthony Nuzzaci

Alexander Vidlak Evers

Diane Kathleen Stille

Kevin J Clair

Richard G Brodeur

A clinical analyzer having the capability to operate at both a higher and lower throughput, depending upon the assay load demand experienced by the hospital or laboratory, so that analyzer throughput most closely matches assay demand.

Clinical analyzer having a variable cycle time and throughput

A pre-processor for use in performing heterogeneous immunoassays on samples for analytes in the sample employing concentrically positioned incubating and processing carousels. A single transfer station permits reaction vessels containing sample and reagents to be moved between the carousels. The samples are separated, washed and mixed on the processing carousel and incubated on the incubating carousel thus speeding up processing throughput.

Method and apparatus for pre-treating samples in an automatic chemical

Assays for separating magnetic particles include separating magnetically responsive particles from a liquid dispersion disposed in a plurality of reaction vessels, and transporting the reaction vessels in sequence past at least one processing position. A robotics reagent arm and probe dispense reagents into the reaction vessels and a reaction monitoring device is capable of relative movement with respect to the transporting device. Incomplete separation is effected by positioning a magnetic field in contact with the reaction vessel for a first shortened time interval during which the particles partially aggregate and afterwards are removed from the reaction vessel. The magnet is repositioned in contact with the reaction vessel for a third time interval to achieve full separation of particles from the liquid.

Apparatus and method for reagent separation in a chemical analyzer

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Wilmington, DE, United States of America

Joseph Edward Kegelman