Rutgers, The State University of New Jersey

University of Medicine and Dentistry of New Jersey

Joseph E Rice

Edmond Joseph LaVoie

Leroy Fong Liu

Daniel S Pilch

Suzanne G Rzuczek

Satyanarayana Mavurapu

The invention provides compounds of formula I, II, and III as defined herein, as well as salts thereof. The compounds may have activity as anti-proliferative agents.

Therapeutic compounds

The invention provides compounds of formula (I) wherein u, d, v, m, n, R, W, X, Y, and Z have any values defined herein, as well as salts thereof. The compounds have activity as anti-proliferative agents. 

The invention provides compounds of formula (I) wherein A, B, R, F, G, n, n' and the dotted line have any values defined herein, as well as salts thereof. The compounds have activity as anti-proliferative agents. 

Macrocyclic polyoxazole compounds and use thereof

The invention provides compounds of formula I: wherein A, B, D, E, R, R, R, R, R, X, and - - - have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabilizers and as anti-proliferative agents.

The invention provides compounds of formula I: wherein A, B, D, E, R, R, R, R, R, X, and ----- have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabilizers and as anti-proliferative agents.

Growing community of inventors

New Brunswick, NJ, United States of America

Joseph E Rice