Duke University

Joseph E Lucas

Geoffrey S Ginsburg

Christopher W Woods

Jen-Tsan Ashley Chi

Ephraim L Tsalik

Thomas L Ortel

Vance Fowler

Sun Hee Ahn

Richard C Becker

Deepak Voora

Lawrence L Carin

Ricardo Henao Giraldo

Thomas W Burke

Alfred Hero

John P Chute

Joseph R Nevins

Holly K Dressman

Erik Soderblom

Aimee K Zaas

The present disclosure provides methods for determining the presence or absence of and/or the etiology of an acute respiratory viral infection in a subject, as well as methods of treating the subject based on the determination, by measuring on a platform the expression levels of a pre-defined set of gene products.

Nasopharyngeal protein biomarkers of acute respiratory virus infection and methods of using same

Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to antiplatelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.

Diagnostic markers for platelet function and methods of use

Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.

Biomarkers for the molecular classification of bacterial infection

The present invention relates, in general, to gene expression profiles, and in particular, to a gene expression profile of an environmental exposure, ionizing radiation. The invention further relates to methods of screening patients for radiation exposure based on gene expression profiling and to kits suitable for use in such methods.

Signatures of radiation response

Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to anti-platelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.

Methods of identifying infectious disease infection prior to presentation of symptoms, assays for identifying genomic markers of infectious disease, and methods for diagnosing the underlying etiology of infectious disease.

Methods of identifying infectious disease and assays for identifying infectious disease

Growing community of inventors

Chapel Hill, NC, United States of America

Joseph E Lucas